Diazoxide Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 1, 2020.
For the Consumer
Applies to diazoxide: oral suspension
Side effects requiring immediate medical attention
Along with its needed effects, diazoxide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking diazoxide:
- Chest pain
Incidence not known
- Abdominal or stomach pain
- black, tarry stools
- blood in the urine
- bloody nose
- blurred vision
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- dry mouth
- extreme thirst
- fast, irregular, pounding, or racing heartbeat or pulse
- flushed, dry skin
- fruit-like breath odor
- heavier menstrual periods
- increased hunger
- increased thirst
- increased urination
- loss of consciousness
- pinpoint red spots on the skin
- skin rash
- troubled breathing
- unexplained weight loss
- unusual bleeding or bruising
- unusual tiredness or weakness
- urinating large amounts or urinating very little
Side effects not requiring immediate medical attention
Some side effects of diazoxide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Increased hair growth, especially on the forehead, back, arms, and legs
Incidence not known
- Loss of appetite
- loss of taste
- weight loss
For Healthcare Professionals
Applies to diazoxide: compounding powder, injectable solution, oral capsule, oral suspension
Angina with myocardial and cerebral infarction have been associated with the use of a 300 mg intravenous dose of diazoxide.
One case of optic nerve infarction was reported following a single 300 mg bolus dose of diazoxide, as a result of a sudden reduction in diastolic pressure.
Results from one prospective trial conducted in patients with severe hypertension and coronary artery disease showed a 50% incidence of ischemic changes in the electrocardiogram following single 300 mg bolus injections of diazoxide.[Ref]
Common (1% to 10%): Increased levels of serum uric acid
Frequency not reported: Weakness, malaise, fever[Ref]
Frequency not reported: Decreased IgG, monilial dermatitis, herpes[Ref]
Frequency not reported: Advance in bone age[Ref]
Frequency not reported: Transient cataracts, subconjunctival hemorrhage, ring scotoma, blurred vision, diplopia, lacrimation[Ref]
Frequency not reported: Increased AST, increased alkaline phosphatase[Ref]
Frequently asked questions
- Should you use a diuretic with diazoxide?
- How does diazoxide (Proglycem) cause hyperglycemia?
- Is diazoxide a vasodilator?
- How does diazoxide slow insulin?
More about diazoxide
- During Pregnancy
- Dosage Information
- Patient Tips
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: agents for hypertensive emergencies
- Other brands
Related treatment guides
1. "Product Information. Proglycem (diazoxide)." Teva Pharmaceuticals USA, North Wales, PA.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.