Trandate

Generic name: labetalol (oral/injection) [ la-BAY-ta-lol ]
Drug class: Non-cardioselective beta blockers

Medically reviewed by Drugs.com on Aug 1, 2023. Written by Cerner Multum.

What is Trandate?

Trandate is a beta-blocker that is used to treat hypertension (high blood pressure). This medicine oral is sometimes given with other blood pressure medications.

Trandate injection is used when hypertension is severe.

Trandate may also be used for purposes not listed in this medication guide.

Trandate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Trandate may cause serious side effects. Call your doctor at once if you have:

• a light-headed feeling, like you might pass out;

• slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);

• shortness of breath (even with mild exertion), swelling, rapid weight gain;

• severe headache, blurred vision, pounding in your neck or ears; or

• liver problems--loss of appetite, stomach pain (upper right side), flu-like symptoms, itching, dark urine, jaundice (yellowing of the skin or eyes).

Severe dizziness or fainting may be more likely in older adults.

Common side effects of Trandate may include:

• dizziness, drowsiness, tiredness;

• nausea, vomiting;

• sudden warmth, skin redness, sweating;

• numbness; or

• tingly feeling in your scalp.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use Trandate if you are allergic to it, or if you have:

• asthma;

• "AV block" (2nd or 3rd degree);

• uncontrolled heart failure;

• very low blood pressure;

• slow heartbeats that have caused you to faint; or

• if your heart cannot pump blood properly.

Tell your doctor if you have ever had:

• congestive heart failure;

• angina (chest pain);

• liver disease;

• emphysema, chronic bronchitis, or other breathing problems;

• pheochromocytoma (tumor of the adrenal gland);

• diabetes;

• coronary artery bypass surgery (sometimes called "CABG");

• kidney disease; or

• allergies.

Trandate can affect your pupils. If you need eye surgery, tell the surgeon about your use of Trandate, even if you no longer take it.

Trandate may cause low blood pressure, low blood sugar, slow heartbeats, or breathing problems in a newborn if the mother uses this medicine during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Not approved for use by anyone younger than 18 years old.

How should I use Trandate?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Trandate oral is taken by mouth.

Trandate injection is given in a vein by a healthcare provider when hypertension is severe. After the injection you may need to remain lying down for up to 3 hours. You may feel light-headed when you first stand up.

Your blood pressure will need to be checked often, and you may need other medical tests. If you have diabetes, check your blood sugar regularly.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms.

Trandate can cause false results with certain lab tests of the urine, including a drug-screening urine test. Tell the laboratory staff that you use this medicine.

Tell your doctor if you have a planned surgery.

You should not stop using Trandate suddenly. Stopping suddenly may make your condition worse.

Store at room temperature away from moisture and heat.

Related/similar drugs

amlodipine, lisinopril, metoprolol, losartan, furosemide, hydrochlorothiazide, propranolol, hydralazine, bisoprolol, enalapril

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include slow heart rate, wheezing, chest tightness, trouble breathing, extreme dizziness, seizure, or fainting.

What should I avoid while using Trandate?

Avoid driving or hazardous activity until you know how Trandate will affect you. Your reactions could be impaired.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of labetalol.

What other drugs will affect Trandate?

Tell your doctor about all your other medicines, especially:

• any other blood pressure medicine;

• aminophylline, theophylline;

• cimetidine;

• heart medication;

• insulin or oral diabetes medicine;

• an antidepressant--amitriptyline, doxepin, desipramine, imipramine, nortriptyline, and others; or

• a bronchodilator--albuterol, formoterol, levalbuterol, metaproterenol, olodaterol, salmeterol, and others.

This list is not complete. Other drugs may affect Trandate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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