Dextromethorphan / phenylephrine / pyrilamine Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 30, 2022.
Applies to dextromethorphan/phenylephrine/pyrilamine: oral liquid, oral suspension, oral suspension extended release, oral syrup, oral tablet chewable, oral tablet chewable extended release
Cardiovascular
Cardiovascular side effects including arrhythmias, hypertension, hypotension, and palpitations have been reported.[Ref]
Nervous system
Nervous system side effects including coordination disturbances, drowsiness, dysphoria, euphoria, headache, insomnia, irritability, nervousness, sedation, and seizures have been reported.[Ref]
Dermatologic
Dermatologic side effects including photosensitivity, pruritus, rash, and urticaria have been reported.[Ref]
Gastrointestinal
Gastrointestinal side effects including constipation, diarrhea, epigastric discomfort, nausea, vomiting, and xerostomia have been reported.[Ref]
Genitourinary
Genitourinary side effects including difficult urination and urinary frequency have been reported.[Ref]
Hematologic
Hematologic side effects including agranulocytosis, hemolytic anemia, and thrombocytopenia have been reported.[Ref]
Musculoskeletal
Neuromuscular side effects including tremor and weakness have been reported.[Ref]
Ocular
Ocular side effects including visual disturbances have been reported.[Ref]
Respiratory
Respiratory side effects including shortness of breath and wheezing have been reported.[Ref]
More about dextromethorphan / phenylephrine / pyrilamine
- Drug interactions
- Dosage information
- During pregnancy
- Reviews (2)
- Drug class: upper respiratory combinations
Patient resources
Other brands
Related treatment guides
References
1. "Product Information. Viravan-DM (dextromethorphan / phenylephrine / pyrilamine)." PediaMed Pharmaceuticals Inc (2003):
2. "Product Information. Codal-DM Syrup (dextromethorphan / phenylephrine / pyrilamine)." Cypress Pharmaceutical Inc (2005):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.