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Dextromethorphan / Phenylephrine / Pyrilamine Dosage

Medically reviewed by Drugs.com. Last updated on Nov 6, 2023.

Applies to the following strengths: 10 mg-5 mg-8.33 mg/5 mL; 15 mg-10 mg-16 mg; 25 mg-12.5 mg-30 mg/5 mL; 15 mg-5 mg-16 mg/5 mL; 15 mg-7.5 mg-12.5 mg/5 mL; 7.5 mg-5 mg-12.5 mg/5 mL; 25 mg-25 mg-30 mg; 25 mg-15.5 mg-15.5 mg/5 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Adult Dose for Cold Symptoms

Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Adult Dose for Sinusitis

Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Pediatric Dose for Allergic Rhinitis

2 years to <6 years:
Suspension: 2.5 mL orally every 12 hours.
Tablet: 1/2 tablet orally every 12 hours.
Liquid: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mg of phenylephrine in 24 hours.

6 years to <12 years:
Suspension: 5 mL orally every 12 hours.
Tablet: 1/2 to 1 tablet orally every 12 hours.
Liquid: 5 mL orally every 4 to 6 hours, not to exceed 30 mg of phenylephrine in 24 hours.

=>12 years:
Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Pediatric Dose for Cold Symptoms

2 years to <6 years:
Suspension: 2.5 mL orally every 12 hours.
Tablet: 1/2 tablet orally every 12 hours.
Liquid: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mg of phenylephrine in 24 hours.

6 years to <12 years:
Suspension: 5 mL orally every 12 hours.
Tablet: 1/2 to 1 tablet orally every 12 hours.
Liquid: 5 mL orally every 4 to 6 hours, not to exceed 30 mg of phenylephrine in 24 hours.

=>12 years:
Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Pediatric Dose for Sinusitis

2 years to <6 years:
Suspension: 2.5 mL orally every 12 hours.
Tablet: 1/2 tablet orally every 12 hours.
Liquid: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mg of phenylephrine in 24 hours.

6 years to <12 years:
Suspension: 5 mL orally every 12 hours.
Tablet: 1/2 to 1 tablet orally every 12 hours.
Liquid: 5 mL orally every 4 to 6 hours, not to exceed 30 mg of phenylephrine in 24 hours.

=>12 years:
Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.