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Dextromethorphan / Phenylephrine / Pyrilamine Dosage

Medically reviewed by Drugs.com. Last updated on Nov 6, 2023.

Applies to the following strengths: 10 mg-5 mg-8.33 mg/5 mL; 15 mg-10 mg-16 mg; 25 mg-12.5 mg-30 mg/5 mL; 15 mg-5 mg-16 mg/5 mL; 15 mg-7.5 mg-12.5 mg/5 mL; 7.5 mg-5 mg-12.5 mg/5 mL; 25 mg-25 mg-30 mg; 25 mg-15.5 mg-15.5 mg/5 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Adult Dose for Cold Symptoms

Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Adult Dose for Sinusitis

Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Pediatric Dose for Allergic Rhinitis

2 years to <6 years:
Suspension: 2.5 mL orally every 12 hours.
Tablet: 1/2 tablet orally every 12 hours.
Liquid: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mg of phenylephrine in 24 hours.

6 years to <12 years:
Suspension: 5 mL orally every 12 hours.
Tablet: 1/2 to 1 tablet orally every 12 hours.
Liquid: 5 mL orally every 4 to 6 hours, not to exceed 30 mg of phenylephrine in 24 hours.

=>12 years:
Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Pediatric Dose for Cold Symptoms

2 years to <6 years:
Suspension: 2.5 mL orally every 12 hours.
Tablet: 1/2 tablet orally every 12 hours.
Liquid: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mg of phenylephrine in 24 hours.

6 years to <12 years:
Suspension: 5 mL orally every 12 hours.
Tablet: 1/2 to 1 tablet orally every 12 hours.
Liquid: 5 mL orally every 4 to 6 hours, not to exceed 30 mg of phenylephrine in 24 hours.

=>12 years:
Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Usual Pediatric Dose for Sinusitis

2 years to <6 years:
Suspension: 2.5 mL orally every 12 hours.
Tablet: 1/2 tablet orally every 12 hours.
Liquid: 2.5 mL orally every 4 to 6 hours, not to exceed 15 mg of phenylephrine in 24 hours.

6 years to <12 years:
Suspension: 5 mL orally every 12 hours.
Tablet: 1/2 to 1 tablet orally every 12 hours.
Liquid: 5 mL orally every 4 to 6 hours, not to exceed 30 mg of phenylephrine in 24 hours.

=>12 years:
Suspension: 5 to 10 mL orally every 12 hours.
Tablet: 1 to 2 tablets orally every 12 hours.
Liquid: 5 to 10 mL orally every 4 to 6 hours, not to exceed 60 mg of phenylephrine in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.