Cozaar Side Effects
Generic name: losartan
Medically reviewed by Drugs.com. Last updated on Oct 26, 2022.
Note: This document contains side effect information about losartan. Some dosage forms listed on this page may not apply to the brand name Cozaar.
Summary
Common side effects of Cozaar include: asthenia, chest pain, diarrhea, fatigue, and hypoglycemia. Other side effects include: hyperkalemia, hypotension, and orthostatic hypotension. Continue reading for a comprehensive list of adverse effects.
Applies to losartan: oral extemporaneous suspension, oral tablets.
Warning
Side effects include:
Patients with hypertension: upper respiratory infection, dizziness, nasal congestion, back pain, leg pain, muscle cramp, sinusitis.
Patients with diabetic nephropathy: Urinary tract infection, diarrhea, anemia, asthenia/fatigue, hypoglycemia, chest pain, cough, bronchitis, diabetic vascular disease, influenza-like disease, cataracts, cellulitis, hyperkalemia, hypotension, muscular weakness, sinusitis, gastritis, hypoesthesia, infection, knee pain, and leg pain.
For Healthcare Professionals
Applies to losartan: oral tablet.
General
The most common adverse reactions were upper respiratory infection and dizziness.[Ref]
Respiratory
Common (1% to 10%): Nasal congestion, upper respiratory infection, sinusitis, pharyngitis, cough, sinus disorder
Uncommon (0.1% to 1%): Dyspnea
Frequency not reported: Bronchitis, pharyngeal discomfort, epistaxis, rhinitis, respiratory congestion[Ref]
Gastrointestinal
Common (1% to 10%): Abdominal pain, nausea, diarrhea, dyspepsia
Uncommon (0.1% to 1%): Obstipation, vomiting
Frequency not reported: Constipation, dental pain, dry mouth, flatulence, gastritis[Ref]
Musculoskeletal
Common (1% to 10%): Muscle cramp, back pain, leg pain, myalgia
Frequency not reported: Arm pain, hip pain, joint swelling, knee pain, musculoskeletal pain, shoulder pain, stiffness, arthralgia, arthritis, fibromyalgia, muscle weakness
Postmarketing reports: Rhabdomyolysis[Ref]
Renal
Common (1% to 10%): Renal impairment, renal failure, BUN increased, serum creatinine increased[Ref]
Nervous system
Common (1% to 10%): Dizziness, headache, vertigo
Uncommon (0.1% to 1%): Somnolence
Rare (less than 0.1%): Paresthesia, syncope, cerebrovascular accident
Frequency not reported: Ataxia, hypesthesia, memory impairment, migraine, peripheral neuropathy, tremor, taste perversion, tinnitus[Ref]
Other
Common (1% to 10%): Asthenia/fatigue, edema/swelling, chest pain
Frequency not reported: Facial edema, fever, orthostatic effects
Postmarketing reports: Malaise[Ref]
Metabolic
Common (1% to 10%): Hyperkalemia, serum potassium increased, hypoglycemia
Frequency not reported: Anorexia, gout
Postmarketing reports: Hyponatremia[Ref]
Cardiovascular
Common (1% to 10%): Orthostatic hypotension
Uncommon (0.1% to 1%): Palpitation, angina pectoris
Rare (less than 0.1%): Atrial fibrillation
Frequency not reported: Second degree atrioventricular block, hypotension, myocardial infarction, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation, flushing
Postmarketing reports: Vasculitis[Ref]
Psychiatric
Common (1% to 10%): Insomnia
Uncommon (0.1% to 1%): Sleep disorder
Frequency not reported: Anxiety, anxiety disorder, confusion, depression, dream abnormality, libido decreased, nervousness, panic disorder[Ref]
Hematologic
Common (1% to 10%): Anemia
Rare (less than 0.1%): Hemolysis
Postmarketing reports: Thrombocytopenia, hemoglobin decreased, hematocrit decreased[Ref]
Dermatologic
Uncommon (0.1% to 1%): Urticaria, pruritus, rash
Rare (less than 0.1%): Angioedema, superficial peeling of palms
Frequency not reported: Alopecia, dermatitis, dry skin, ecchymosis, erythema, photosensitivity, sweating
Postmarketing reports: Erythroderma[Ref]
Hepatic
Rare (less than 0.1%): ALT increased
Postmarketing reports: Hepatitis, liver enzymes increased, serum bilirubin increased, pancreatitis, liver function abnormalities[Ref]
Genitourinary
Frequency not reported: Impotence, nocturia, urinary frequency, urinary tract infection[Ref]
Ocular
Frequency not reported: Blurred vision, burning/stinging in the eye, conjunctivitis, visual acuity decreased[Ref]
Immunologic
Frequency not reported: Flu-like symptoms
Postmarketing reports: Anaphylactic reactions, hypersensitivity reactions[Ref]
Frequently asked questions
- Can you eat bananas when taking losartan?
- Does Losartan block the receptor used by the Coronavirus?
- Losartan vs Valsartan - What's the difference between them?
- Does losartan cause rapid heart rate, irregular heartbeat or low blood pressure?
- Are losartan and losartan potassium the same or different drugs?
More about Cozaar (losartan)
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References
1. Product Information. Cozaar (losartan). Merck & Co., Inc. 2001.
2. Cerner Multum, Inc. UK Summary of Product Characteristics.
3. Cerner Multum, Inc. Australian Product Information.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.