Corlanor Side Effects

Generic name: ivabradine

Medically reviewed by Drugs.com. Last updated on Feb 5, 2024.

Note: This document provides detailed information about Corlanor Side Effects associated with ivabradine. Some dosage forms listed on this page may not apply specifically to the brand name Corlanor.

Applies to ivabradine: oral solution, oral tablet.

Serious side effects of Corlanor

Along with its needed effects, ivabradine (the active ingredient contained in Corlanor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ivabradine:

More common side effects

• blurred vision
• chest pain or discomfort
• fast or irregular heartbeat
• headache
• lightheadedness, dizziness, or fainting
• nervousness
• pounding in the ears
• slow or irregular heartbeat
• unusual tiredness

Incidence not known

• confusion
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• hives or welts, itching, or skin rash
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
• sweating

Other side effects of Corlanor

Some side effects of ivabradine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

• seeing flashes of light

Incidence not known

• double vision
• feeling of constant movement of self or surroundings
• flushing or redness of the skin
• seeing double
• sensation of spinning
• trouble seeing
• unusually warm skin

For healthcare professionals

Applies to ivabradine: oral liquid, oral tablet.

General adverse events

The most common side effects were cardiac failure, phosphene-like events, and bradycardia.^[Ref]

Cardiovascular

• Very common (10% or more): Cardiac failure (21.7%), bradycardia (up to 10%)
• Common (1% to 10%): Hypertension, blood pressure increased, atrial fibrillation, ventricular extrasystoles, atrioventricular block first degree, unstable angina, angina pectoris aggravated, myocardial ischemia, blood pressure inadequately controlled, sinus tachycardia, supraventricular extrasystoles, atrial flutter, ventricular tachycardia, bradycardia symptomatic, bradycardia asymptomatic, angina pectoris, acute myocardial infarction, myocardial infarction, hypotension, sudden cardiac death
• Uncommon (0.1% to 1%): Palpitations, sinus arrhythmia, ECG prolonged QT interval
• Very rare (less than 0.01%): Atrioventricular block second degree, atrioventricular block third degree, sick sinus syndrome
• Postmarketing reports: Torsade de pointes, ventricular fibrillation^[Ref]

Ocular

• Very common (10% or more): Phosphene-like events (14.5%)
• Common (1% to 10%): Phosphenes, visual brightness, blurred vision
• Uncommon (0.1% to 1%): Diplopia, visual impairment^[Ref]

Phosphenes generally occur within the first 2 months of treatment and may occur repeatedly afterward. They were generally reported as mild to moderate in intensity and led to discontinuation in less than 1% of patients. Most cases resolved during or after treatment.^[Ref]

Respiratory

• Common (1% to 10%): Pneumonia, bronchitis acute, bronchitis, nasopharyngitis, upper respiratory tract infection, respiratory tract infection, influenza, cough, chronic obstructive pulmonary disease
• Uncommon (0.1% to 1%): Dyspnea^[Ref]

Metabolic

• Common (1% to 10%): Diabetes mellitus inadequately controlled, diabetes mellitus, hypercholesterolemia, hypokalemia, hyperuricemia^[Ref]

Nervous system

• Common (1% to 10%): Headache, dizziness, ischemic stroke
• Uncommon (0.1% to 1%): Syncope^[Ref]

Other

• Common (1% to 10%): Sudden death, fall
• Uncommon (0.1% to 1%): Vertigo, asthenia, fatigue
• Rare (less than 0.1%): Malaise^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, gastritis
• Uncommon (0.1% to 1%): Nausea, constipation, abdominal pain^[Ref]

Hematologic

• Common (1% to 10%): Blood creatinine increased, anemia
• Uncommon (0.1% to 1%): Eosinophilia^[Ref]

Renal

• Common (1% to 10%): Renal failure^[Ref]

Hepatic

• Common (1% to 10%): Transaminases increased^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Angioedema, rash
• Rare (less than 0.1%): Erythema, pruritus, urticaria^[Ref]

Musculoskeletal

• Uncommon (0.1% to 1%): Muscle cramps^[Ref]

Further information

Corlanor side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer