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Corlanor Side Effects

Generic Name: ivabradine

Note: This page contains information about the side effects of ivabradine. Some of the dosage forms included on this document may not apply to the brand name Corlanor.

In Summary

Common side effects of Corlanor include: bradycardia. Other side effects include: atrial fibrillation. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to ivabradine: oral tablet

In addition to its needed effects, some unwanted effects may be caused by ivabradine (the active ingredient contained in Corlanor). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking ivabradine:

More common:
  • Blurred vision
  • chest pain or discomfort
  • dizziness
  • fainting
  • fast or irregular heartbeat
  • headache
  • lightheadedness, dizziness, or fainting
  • nervousness
  • pounding in the ears
  • shortness of breath
  • slow or irregular heartbeat
  • unusual tiredness
Incidence not known:
  • Confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • sweating

Minor Side Effects

Some of the side effects that can occur with ivabradine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Seeing flashes of light
Incidence not known:
  • Double vision
  • feeling of constant movement of self or surroundings
  • flushing or redness of the skin
  • hives or welts, itching, or skin rash
  • seeing double
  • sensation of spinning
  • trouble seeing
  • unusually warm skin

For Healthcare Professionals

Applies to ivabradine: oral tablet


The most common side effects were cardiac failure, phosphene-like events, and bradycardia.[Ref]


Very common (10% or more): Cardiac failure (21.7%), bradycardia (up to 10%)
Common (1% to 10%): Hypertension, blood pressure increased, atrial fibrillation, ventricular extrasystoles, atrioventricular block first degree, unstable angina, angina pectoris aggravated, myocardial ischemia, blood pressure inadequately controlled, sinus tachycardia, supraventricular extrasystoles, atrial flutter, ventricular tachycardia, bradycardia symptomatic, bradycardia asymptomatic, angina pectoris, acute myocardial infarction, myocardial infarction, hypotension, sudden cardiac death
Uncommon (0.1% to 1%): Palpitations, sinus arrhythmia, ECG prolonged QT interval
Very rare (less than 0.01%): Atrioventricular block second degree, atrioventricular block third degree, sick sinus syndrome
Postmarketing reports: Torsade de pointes, ventricular fibrillation[Ref]


Very common (10% or more): Phosphene-like events (14.5%)
Common (1% to 10%): Phosphenes, visual brightness, blurred vision
Uncommon (0.1% to 1%): Diplopia, visual impairment[Ref]

Phosphenes generally occur within the first 2 months of treatment and may occur repeatedly afterward. They were generally reported as mild to moderate in intensity and led to discontinuation in less than 1% of patients. Most cases resolved during or after treatment.[Ref]


Common (1% to 10%): Pneumonia, bronchitis acute, bronchitis, nasopharyngitis, upper respiratory tract infection, respiratory tract infection, influenza, cough, chronic obstructive pulmonary disease
Uncommon (0.1% to 1%): Dyspnea[Ref]


Common (1% to 10%): Diabetes mellitus inadequately controlled, diabetes mellitus, hypercholesterolemia, hypokalemia, hyperuricemia[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness, ischemic stroke
Uncommon (0.1% to 1%): Syncope[Ref]


Common (1% to 10%): Sudden death, fall
Uncommon (0.1% to 1%): Vertigo, asthenia, fatigue
Rare (less than 0.1%): Malaise[Ref]


Common (1% to 10%): Diarrhea, gastritis
Uncommon (0.1% to 1%): Nausea, constipation, abdominal pain[Ref]


Common (1% to 10%): Blood creatinine increased, anemia
Uncommon (0.1% to 1%): Eosinophilia[Ref]


Common (1% to 10%): Renal failure[Ref]


Common (1% to 10%): Transaminases increased[Ref]


Uncommon (0.1% to 1%): Angioedema, rash
Rare (less than 0.1%): Erythema, pruritus, urticaria[Ref]


Uncommon (0.1% to 1%): Muscle cramps[Ref]


1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Corlanor (ivabradine)." Amgen USA, Thousand Oaks, CA.

Not all side effects for Corlanor may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.