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Centany AT Side Effects

Generic Name: mupirocin topical

Note: This page contains information about the side effects of mupirocin topical. Some of the dosage forms included on this document may not apply to the brand name Centany AT.

For the Consumer

Applies to mupirocin topical: topical cream, topical ointment

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by mupirocin topical (the active ingredient contained in Centany AT). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking mupirocin topical:

Less common:
  • Burning, stinging, or pain on the application site
Rare
  • Blistering, crusting, irritation, itching, or reddening of the skin
  • canker sores
  • cracked, dry, scaly skin
  • pain, swelling, tenderness, warmth on the skin
  • sores, ulcers, or white spots on the lips or tongue or inside the mouth
Incidence not known:
  • Abdominal or stomach tenderness
  • cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • fever
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • severe abdominal or stomach cramps and pain
  • tightness in the chest
  • unusual tiredness or weakness
  • watery and severe diarrhea, which may also be bloody

Minor Side Effects

Some of the side effects that can occur with mupirocin topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Headache
  • nausea

For Healthcare Professionals

Applies to mupirocin topical: compounding powder, nasal ointment, topical cream, topical kit, topical ointment

Dermatologic

Nasal Ointment: Cutaneous hypersensitivity reactions have been reported very rarely during postmarketing experience.

Topical Ointment: Cutaneous sensitization reactions to the active component or ointment base have been reported.[Ref]

Nasal Ointment:
-Uncommon (0.1% to 1%): Pruritus/itching
-Frequency not reported: Rash
-Postmarketing reports: Cutaneous hypersensitivity reactions

Topical Cream:
-Common (1% to 10%): Rash, pruritus, cutaneous hypersensitivity reactions
-Frequency not reported: Dry skin, erythema, cellulitis, dermatitis, hives

Topical Ointment:
-Common (1% to 10%): Pruritus/itching, erythema, dry skin/dryness
-Uncommon (0.1% to 1%): Contact dermatitis, furunculosis, exfoliative dermatitis, rash, cutaneous sensitization reactions[Ref]

Gastrointestinal

Frequency not reported: Clostridium difficile-associated diarrhea

Nasal Ointment:
-Frequency not reported: Diarrhea, dry mouth, nausea

Topical Cream:
-Common (1% to 10%): Diarrhea, nausea
-Frequency not reported: Abdominal pain, ulcerative stomatitis

Topical Ointment:
-Frequency not reported: Nausea[Ref]

Hypersensitivity

Postmarketing reports: Systemic allergic reactions (e.g., anaphylaxis, generalized rash, urticaria, angioedema)[Ref]

Systemic allergic reactions have been reported during postmarketing experience very rarely.[Ref]

Local

Nasal Ointment:
-Common (1% to 10%): Burning, irritation, tingling, itching, stinging, soreness, facial pain over maxillae

Topical Cream:
-Common (1% to 10%): Application site reactions, application site burning, application site hypersensitivity reactions (including urticaria, pruritus, erythema, burning sensation, contact dermatitis, rash)

Topical Ointment:
-Common (1% to 10%): Burning, stinging, pain/swelling at application site, dryness, itching, erythema
-Frequency not reported: Increased exudate, application site reactions[Ref]

Nervous system

Nasal Ointment:
-Common (1% to 10%): Taste perversion, headache

Topical Cream:
-Common (1% to 10%): Headache
-Frequency not reported: Dizziness[Ref]

Ocular

Nasal Ointment:
-Common (1% to 10%): Conjunctivitis
-Frequency not reported: Blepharitis, burning, tearing[Ref]

Other

Nasal Ointment:
-Common (1% to 10%): Burning/stinging
-Frequency not reported: Ear pain

Topical Cream:
-Frequency not reported: Bleeding or pain secondary to eczema, secondary wound infection

Topical Ointment:
-Common (1% to 10%): Burning/stinging/pain
-Rare (0.01% to 0.1%): Systemic reactions (not otherwise specified)
-Frequency not reported: Tenderness, swelling, increased exudate[Ref]

Respiratory

Nasal Ointment:
-Common (1% to 10%): Postnasal drip, sinusitis, rhinitis, respiratory disorder (including upper respiratory tract congestion), pharyngitis, cough
-Uncommon (0.1% to 1%): Nasal mucosa reactions
-Frequency not reported: Epistaxis[Ref]

References

1. "Product Information. Bactroban (mupirocin)." SmithKline Beecham, Philadelphia, PA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Bactroban (mupirocin)." SmithKline Beecham, Philadelphia, PA.

5. "Product Information. Bactroban Nasal (mupirocin topical)." SmithKline Beecham, Philadelphia, PA.

Not all side effects for Centany AT may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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