Bevespi Aerosphere Side Effects
Generic name: formoterol / glycopyrrolate
Medically reviewed by Drugs.com. Last updated on Jan 31, 2025.
Note: This document provides detailed information about Bevespi Aerosphere.
Applies to formoterol / glycopyrrolate: inhalation aerosol powder Side Effects associated with formoterol / glycopyrrolate. Some dosage forms listed on this page may not apply specifically to the brand name Bevespi Aerosphere.
Applies to formoterol / glycopyrrolate: inhalation aerosol powder.
Precautions
It is very important that your doctor check your progress at regular visits to make sure the medicine is working properly. Blood and urine tests may be needed to check for any unwanted effects.
Tell your doctor if you are also using any other medicine for your COPD. Your doctor may want you to use it only during a severe COPD attack. Follow your doctor's instructions on how you should take your medicine.
This medicine should not be used if you are having a sudden COPD attack, or if symptoms of COPD attack has already started. Your doctor will give you a short-acting inhaler to use for this condition. If the short-acting inhaler is not working, tell your doctor right away.
Talk to your doctor or get medical care right away if:
- Your symptoms do not improve after using this medicine for a few days or if they become worse.
- Your short-acting inhaler does not seem to be working as well as usual and you need to use it more often.
Do not use this medicine together with other inhaled medicines for COPD, including arformoterol (Brovana®), budesonide/formoterol (Symbicort®), formoterol (Foradil®, Perforomist®), indacaterol (Arcapta® Neohaler®), salmeterol (Serevent®), or vilanterol.
This medicine may increase the risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take this medicine without an inhaled steroid medicine. Talk to your doctor if you have concerns about this.
This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. This may be a life-threatening situation. Check with your doctor right away if you have a cough, difficulty with breathing, shortness of breath, or wheezing after using this medicine.
If you develop a skin rash, hives, swelling of the tongue, lips, or face, or any allergic reaction to this medicine, check with your doctor right away.
This medicine may cause heart or blood vessel problems, including heart rhythm problems. Check with your doctor right away if you have chest pain or tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, troubled breathing, or weight gain.
Call your doctor right away if blurred vision, difficulty in reading, seeing halos around lights, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).
Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have more than one of the following symptoms: decreased urine, dry mouth, increased thirst, loss of appetite, mood changes, muscle pain or cramps, nausea or vomiting, numbness or tingling in the hands, feet, or lips, seizures, uneven heartbeat, or unusual tiredness or weakness.
This medicine may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
Check with your doctor right away if you have a decrease in urine volume, decrease in the frequency of urination, difficulty in passing urine, or painful urination.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Serious side effects of Bevespi Aerosphere
Along with its needed effects, formoterol/glycopyrrolate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking formoterol / glycopyrrolate:
Less common side effects
- bladder pain
- bloody or cloudy urine
- chest pain
- chills
- cough
- diarrhea
- difficult, burning, or painful urination
- fever
- frequent urge to urinate
- general feeling of discomfort or illness
- headache
- joint pain
- loss of appetite
- lower back or side pain
- muscle aches and pains
- nausea
- pain or tenderness around the eyes and cheekbones
- shivering
- sore throat
- stuffy or runny nose
- sweating
- tightness of the chest
- trouble sleeping
- troubled breathing
- unusual tiredness or weakness
- vomiting
Incidence not known
- agitation
- blurred vision
- decrease in the frequency of urination
- difficulty in passing urine (dribbling)
- dizziness
- dry mouth
- fainting
- fast, pounding, or irregular heartbeat or pulse
- flushed, dry skin
- fruit-like breath odor
- hives or welts, itching, or skin rash
- hoarseness
- increased hunger
- increased thirst
- irritation
- joint stiffness or swelling
- redness of the skin
- restlessness
- stomach pain
- swelling of the eyelids, face, lips, hands, or feet
- tremor
- trouble swallowing
- unexplained weight loss
Other side effects of Bevespi Aerosphere
Some side effects of formoterol / glycopyrrolate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common side effects
- anxiety
- arm or leg pain
- bruise
- difficulty with moving
- falls
- mouth or throat pain
- muscle spasm or stiffness
- toothache
For healthcare professionals
Applies to formoterol / glycopyrrolate: inhalation aerosol.
Respiratory adverse events
- Common (1% to 10%): Cough (4%); In less than 2%: Chest pain, influenza, acute sinusitis[Ref]
Cardiovascular
- Frequency not reported: Formoterol fumarate: Palpitations, cardiac arrhythmias (atrial fibrillation, supraventricular tachycardia, extrasystoles)[Ref]
Gastrointestinal
- Common (1% to 10%): In less than 2%: Tooth abscess, oropharyngeal pain, vomiting, dry mouth
- Frequency not reported: Formoterol fumarate: Nausea[Ref]
Genitourinary
- Common (1% to 10%): Urinary tract infection (2.6%)
- Frequency not reported: Worsening of urinary retention[Ref]
Hypersensitivity
- Frequency not reported: Hypersensitivity reactions (formoterol fumarate)[Ref]
Metabolic
- Frequency not reported: Formoterol fumarate: Hyperglycemia[Ref]
Musculoskeletal
- Common (1% to 10%): In less than 2%: Arthralgia, muscle spasm, pain in the extremity[Ref]
Nervous system
- Common (1% to 10%): In less than 2%: Headache, dizziness
- Frequency not reported: Formoterol fumarate: Tremor[Ref]
Ocular
- Frequency not reported: Worsening of narrow-angle glaucoma[Ref]
Other
- Common (1% to 10%): In less than 2%: Fall, fatigue, contusion[Ref]
Psychiatric
- Common (1% to 10%): Anxiety (less than 2%)
- Frequency not reported: Paradoxical bronchospasm; Formoterol fumarate: Restlessness, sleep disturbances, agitation[Ref]
See also:
Symbicort
Symbicort (budesonide and formoterol) is used to prevent bronchospasm in people with asthma or ...
Ventolin
Ventolin is used for asthma, acute, asthma, maintenance, bronchiectasis, bronchospasm prophylaxis ...
Breztri Aerosphere
Breztri (budesonide/glycopyrrolate/formoterol fumarate) is a combination inhaler used for the ...
Ventolin HFA
Ventolin HFA (albuterol) is used to treat or prevent breathing problems in patients who have asthma ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Breo Ellipta
Breo Ellipta (fluticasone and vilanterol) is used to prevent airflow obstruction or bronchospasm in ...
Spiriva
Spiriva (tiotropium) is used to prevent bronchospasm in people with bronchitis, emphysema, or COPD ...
Anoro Ellipta
Anoro (umeclidinium and vilanterol inhalation powder) is used to treat chronic obstructive ...
Xopenex
Xopenex is a short-acting bronchodilator used to treat or prevent bronchospasm in asthma and other ...
References
1. (2016) "Product Information. Bevespi Aerosphere (formoterol-glycopyrrolate)." Astra-Zeneca Pharmaceuticals
Frequently asked questions
- Can it be used with a spacer?
- How many puffs are in Bevespi Aerosphere?
- How fast does Bevespi work?
- What type of inhaler is Bevespi Aerosphere?
- How do you use Bevespi Aerosphere?
More about Bevespi Aerosphere (formoterol / glycopyrrolate)
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Further information
Bevespi Aerosphere side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.