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Bevespi Aerosphere Side Effects

Generic name: formoterol / glycopyrrolate

Medically reviewed by Drugs.com. Last updated on Jan 31, 2025.

Note: This document provides detailed information about Bevespi Aerosphere.

Applies to formoterol / glycopyrrolate: inhalation aerosol powder Side Effects associated with formoterol / glycopyrrolate. Some dosage forms listed on this page may not apply specifically to the brand name Bevespi Aerosphere.

Applies to formoterol / glycopyrrolate: inhalation aerosol powder.

Precautions

It is very important that your doctor check your progress at regular visits to make sure the medicine is working properly. Blood and urine tests may be needed to check for any unwanted effects.

Tell your doctor if you are also using any other medicine for your COPD. Your doctor may want you to use it only during a severe COPD attack. Follow your doctor's instructions on how you should take your medicine.

This medicine should not be used if you are having a sudden COPD attack, or if symptoms of COPD attack has already started. Your doctor will give you a short-acting inhaler to use for this condition. If the short-acting inhaler is not working, tell your doctor right away.

Talk to your doctor or get medical care right away if:

Do not use this medicine together with other inhaled medicines for COPD, including arformoterol (Brovana®), budesonide/formoterol (Symbicort®), formoterol (Foradil®, Perforomist®), indacaterol (Arcapta® Neohaler®), salmeterol (Serevent®), or vilanterol.

This medicine may increase the risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take this medicine without an inhaled steroid medicine. Talk to your doctor if you have concerns about this.

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. This may be a life-threatening situation. Check with your doctor right away if you have a cough, difficulty with breathing, shortness of breath, or wheezing after using this medicine.

If you develop a skin rash, hives, swelling of the tongue, lips, or face, or any allergic reaction to this medicine, check with your doctor right away.

This medicine may cause heart or blood vessel problems, including heart rhythm problems. Check with your doctor right away if you have chest pain or tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, troubled breathing, or weight gain.

Call your doctor right away if blurred vision, difficulty in reading, seeing halos around lights, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have more than one of the following symptoms: decreased urine, dry mouth, increased thirst, loss of appetite, mood changes, muscle pain or cramps, nausea or vomiting, numbness or tingling in the hands, feet, or lips, seizures, uneven heartbeat, or unusual tiredness or weakness.

This medicine may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.

Check with your doctor right away if you have a decrease in urine volume, decrease in the frequency of urination, difficulty in passing urine, or painful urination.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Bevespi Aerosphere

Along with its needed effects, formoterol/glycopyrrolate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking formoterol / glycopyrrolate:

Less common side effects

  • bladder pain
  • bloody or cloudy urine
  • chest pain
  • chills
  • cough
  • diarrhea
  • difficult, burning, or painful urination
  • fever
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • shivering
  • sore throat
  • stuffy or runny nose
  • sweating
  • tightness of the chest
  • trouble sleeping
  • troubled breathing
  • unusual tiredness or weakness
  • vomiting

Incidence not known

  • agitation
  • blurred vision
  • decrease in the frequency of urination
  • difficulty in passing urine (dribbling)
  • dizziness
  • dry mouth
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • flushed, dry skin
  • fruit-like breath odor
  • hives or welts, itching, or skin rash
  • hoarseness
  • increased hunger
  • increased thirst
  • irritation
  • joint stiffness or swelling
  • redness of the skin
  • restlessness
  • stomach pain
  • swelling of the eyelids, face, lips, hands, or feet
  • tremor
  • trouble swallowing
  • unexplained weight loss

Other side effects of Bevespi Aerosphere

Some side effects of formoterol / glycopyrrolate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

  • anxiety
  • arm or leg pain
  • bruise
  • difficulty with moving
  • falls
  • mouth or throat pain
  • muscle spasm or stiffness
  • toothache

For healthcare professionals

Applies to formoterol / glycopyrrolate: inhalation aerosol.

Respiratory adverse events

Cardiovascular

Gastrointestinal

Genitourinary

Hypersensitivity

Metabolic

Musculoskeletal

Nervous system

Ocular

Other

Psychiatric

See also:

References

1. (2016) "Product Information. Bevespi Aerosphere (formoterol-glycopyrrolate)." Astra-Zeneca Pharmaceuticals

Frequently asked questions

Further information

Bevespi Aerosphere side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.