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How do you use Bevespi Aerosphere?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on March 15, 2023.

Official answer


To use Bevespi Aerosphere:

  1. Read the step-by-step instructions for using Bevespi Aerosphere found at the end of the Patient Information leaflet found with your inhaler. Read each time you get a refill as there may be new information.
  2. Before the FIRST use of your Bevespi Aerosphere inhaler, prime the inhaler by removing the cap and releasing 4 sprays into the air away from your face (do not inhale them). Shake well before each spray.
  3. Remove the cap from the mouthpiece before each use and shake the inhaler well.
  4. Breathe out as fully as you comfortably can through your mouth.
  5. Close your lips around the mouthpiece and tilt your head back keeping your tongue below the mouthpiece.
  6. While breathing in deeply and slowly, press down on the center of the canister until the canister stops moving and the dose is released.
  7. After the dose, remove the mouthpiece from your mouth and hold your breath as long as you comfortably can, up to 10 seconds, then breath out gently.
  8. Repeat steps 3 through 7 for your second dose of Bevespi Aerosphere.

After cleaning your inhaler each week, and if you do not use your Bevespi Aerosphere for more than 7 days, reprime your Bevespi Aerosphere by releasing 2 puffs into the air away from your face (do not inhale them). Shake well before each spray.

Related: How do I clean my Bevespi Aerosphere? (see Instruction for Use)

Bevespi Aerosphere comes with a dose counter located on the top of the canister that tells you how many puffs of medicine you have left. Follow the instructions enclosed with your inhaler, and if you have questions, ask your pharmacist or doctor. Your healthcare provider can show you how to use the inhaler.

Bevespi Aerosphere (generic name: formoterol fumarate and glycopyrrolate) is a long-acting, fixed dose beta2-adrenergic agonist (LABA) and anticholinergic combination approved for the long-term treatment of chronic obstructive pulmonary disease (COPD).

What is the usual dose for Bevespi Aerosphere?

Bevespi Aerosphere is normally given as 2 inhalations twice a day, in the morning and in the evening, via a pressurized metered dose inhaler. If your doctor's instruction for dosing is different, follow their instructions.

Related: Bevespi Aerosphere dosage (in more detail)

If you miss a dose of Bevespi Aerosphere, take your next dose at the same time you normally do. Do not take more than your prescribed dose of Bevespi Aerosphere.

Continue using Bevespi Aerosphere as directed until your doctor tells you stop. If you stop treatment on your own your symptoms may return.

Bevespi Aerosphere is NOT used to treat sudden breathing problems of COPD or for asthma. A fast-acting inhaler like albuterol is used for sudden breathing problems. Always keep your fast-acting inhaler with you. If you do not have one, call your healthcare provider for a prescription.

Call your healthcare provider or get medical care right away if:

  • your breathing problems get worse
  • you need to use your rescue inhaler more often than usual
  • your rescue inhaler does not work as well to relieve your symptoms.

Do not use other medicines that contain LABAs or anticholinergic medicines for any reason. If you are not sure if your medicines contain these drugs, ask your doctor or pharmacist.

Learn more: COPD: Could you be at risk?

This is not all the information you need to know about Bevespi Aerosphere (formoterol fumarate and glycopyrrolate) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full product information here, and discuss this information and any questions you have with your doctor or other health care provider.


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