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Can you drink alcohol on Dupixent?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Oct 12, 2022.

Official answer


Dupixent has not been reported to have a drug interaction with alcohol.

A few case reports of flushing (facial redness) have been reported by people who used Dupixent and drank alcohol. After Dupixent (generic name: dupilumab) was approved by the FDA and put on the market, side effects like facial rash, redness, swelling, itching, burning and pain were also reported in its package insert. A definite link between alcohol use, Dupixent, and facial skin reactions is not known.

Use of alcohol can also be dangerous if you have liver disease or if you take medicines that can cause liver disease. In long-term studies, Dupixent has not been reported to cause liver toxicity, which could also be worsened by drinking alcohol.

If you choose to drink, it is always best to drink in moderation and check with your healthcare provider if you take any medication. Tell your healthcare provider if you experience any side effect that bothers you or that does not go away. Tell them about all of the medicines you take, including prescription and over-the-counter (OTC) medicines, vitamins, and dietary herbal supplements.

Learn more: Drug Interactions with Dupixent (in more detail)

Is Dupixent steroid-free?

  • Yes, Dupixent (generic name: dupilumab) is a steroid-free, injectable biologic drug. This is an advantage as steroids, often used to lower inflammation (swelling), can cause serious side effects.
  • It is classified as an interleukin-4 (IL-4) receptor alpha antagonist. Dupixent works by lowering inflammation that can lead to symptoms in the various conditns it is approved.

Dupixent is approved by the FDA to treat:

  • eczema or asthma not controlled by other medications, or in chronic rhinosinusitis (long-term sinus inflammation) that is associated with nasal polyps (non-cancerous growths on the sinuses).
  • inflammation and trouble swallowing that can occur in patients with eosinophilic esophagitis (EoE).
  • In Sept. 2022, it was approved for adults as the first treatment for prurigo nodularis, a skin condition that consists of hard and extremely itchy nodules that can worsen and spread.

This is not all the information you need to know about Dupixent (dupilumab) for safe and effective use. Review the full Dupixent product information and discuss this information with your doctor or other health care provider.

  • Igelman SJ, Na C, Simpson EL. Alcohol-induced facial flushing in a patient with atopic dermatitis treated with dupilumab. JAAD Case Rep. 2020;6(2):139-140. Published 2020 Jan 25. doi:10.1016/j.jdcr.2019.12.002
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Dupilumab. [Updated 2018 Aug 1]. Available from:
  • Dupixent (dupilumab) [package insert]. Regeneron Pharmaceuticals. Tarrytown, NY. Accessed June 3, 2022 at
  • Dupixent Monograph. Accessed June 3, 2022 at

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