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How do you use Dupixent?

Medically reviewed by Last updated on Jun 24, 2020.

Official Answer


Dupixent (dupilumab) is a prescription injection used to treat moderate-to-severe eczema in patients 6 years and older, and moderate-to-severe asthma in patients 12 years and older. It is also used to treat adults with chronic rhinosinusitis with nasal polyps.

  • Dupixent comes as a single-dose pre-filled syringe and as a a single-dose pre-filled pen.
  • It is given as a subcutaneous injection by the patient or a caregiver.
    • Dupixent pre-filled pen is only for use in adults and adolescents aged 12 years and older. In adolescent patients, the dose should be administered by, or under the supervision of an adult.
    • Dupixent pre-filled syringe should be given by a caregiver in children 6-11 years of age.
  • The injection can be administered into the thigh or stomach, except for the 2 inches (5 cm) around the belly button. If a caregiver injects the dose, they can also use the outer area of the upper arm.
  • Rotate the injection site with each injection. DO NOT inject Dupixent into skin that is tender, damaged, bruised, or scarred.

See the detailed Instructions for Use leaflet for additional information on how to prepare and inject Dupixent, and how to properly store and dispose of the used pre-filled syringes and pre-filled pens.

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