Skip to main content

Amlodipine / Telmisartan Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 13, 2023.

Applies to amlodipine / telmisartan: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

When pregnancy is detected, discontinue telmisartan/amlodipine as soon as possible.

Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.

Serious side effects

Along with its needed effects, amlodipine / telmisartan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amlodipine / telmisartan:

More common side effects

  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • body aches or pain
  • chills
  • cough
  • difficulty breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • rapid weight gain
  • runny nose
  • sneezing
  • sore throat
  • tingling of the hands or feet
  • unusual tiredness or weakness
  • unusual weight gain or loss

Less common side effects

  • bladder pain
  • bloody or cloudy urine
  • blurred vision
  • chest pain
  • diarrhea
  • difficult, burning, or painful urination
  • dizziness
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • nervousness
  • pounding in the ears
  • shivering
  • slow or fast heartbeat
  • sweating
  • trouble sleeping
  • vomiting

Rare side effects

  • abdominal or stomach pain
  • arm, back, or jaw pain
  • black, tarry stools
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • blood in the urine or stools
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest tightness or heaviness
  • cold sweats
  • confusion
  • constipation
  • cough or hoarseness
  • dark urine
  • difficult or labored breathing
  • difficulty swallowing
  • dry mouth
  • extreme fatigue
  • fast, irregular, pounding, or racing heartbeat or pulse
  • feeling of warmth
  • flushed, dry skin
  • fruit-like breath odor
  • hives
  • increased hunger
  • increased sweating
  • increased thirst
  • increased volume of pale, dilute urine
  • irregular heartbeat
  • irritation in the mouth
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lightheadedness, dizziness, or fainting
  • loss of consciousness
  • muscle cramps or stiffness
  • pale, bluish-colored, or cold hands or feet
  • pinpoint red spots on the skin
  • rash
  • redness and swelling of the gums
  • redness, soreness, or itching skin
  • severe or sudden headache
  • sudden loss of coordination
  • sudden slurring of speech
  • swollen glands
  • tightness in the chest
  • trembling or shaking of the hands or feet
  • unexplained weight loss
  • unusual bleeding or bruising
  • vomiting of blood
  • weakness in the arms, hands, legs, or feet
  • weight gain
  • yellow eyes or skin

Other side effects

Some side effects of amlodipine / telmisartan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

  • acid or sour stomach
  • belching
  • difficulty with moving
  • heartburn
  • indigestion
  • pain or tenderness around the eyes and cheekbones
  • sleepiness or unusual drowsiness

Rare side effects

  • abnormal dreams
  • ankle, knee, or great toe joint pain
  • anxiety
  • bad, unusual, or unpleasant (after) taste
  • bleeding after defecation
  • blistering, crusting, irritation, itching, or reddening of the skin
  • bloody nose
  • burning feeling in the chest or stomach
  • burning, dry, or itching eyes
  • changes in vision
  • cold and clammy skin
  • continuing ringing or buzzing or other unexplained noise in the ears
  • cough producing mucus
  • cracked, dry, or scaly skin
  • decreased sexual performance or desire
  • depression
  • dry mouth
  • earache
  • excess air or gas in the stomach or intestines
  • feeling of constant movement of self or surroundings
  • feeling of warmth
  • full feeling
  • hair loss or thinning of the hair
  • headache, severe and throbbing
  • hearing loss
  • hives or welts
  • hyperventilation
  • inability to have or keep an erection
  • increased appetite
  • irritability
  • lack of feeling or emotion
  • lack or loss of strength
  • loose stools
  • loss of memory
  • redness of the skin
  • redness or swelling in the ear
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • restlessness
  • tenderness in the stomach area
  • toothache
  • uncomfortable swelling around the anus

For healthcare professionals

Applies to amlodipine / telmisartan: oral tablet.

General adverse events

The most common side effect was peripheral edema.[Ref]

Other

Amlodipine:

Telmisartan:

Nervous system

Amlodipine:

Telmisartan:

Musculoskeletal

Amlodipine:

Telmisartan:

Gastrointestinal

Amlodipine:

Telmisartan:

Dermatologic

Amlodipine:

Telmisartan:

Genitourinary

Amlodipine:

Telmisartan:

Cardiovascular

Amlodipine:

Telmisartan:

Respiratory

Amlodipine:

Telmisartan:

Hepatic

Amlodipine:

Telmisartan:

Psychiatric

Amlodipine:

Telmisartan:

Metabolic

Amlodipine:

Telmisartan:

Ocular

Amlodipine:

Telmisartan:

Hematologic

Amlodipine:

Telmisartan:

Immunologic

Amlodipine:

Telmisartan:

Renal

Telmisartan:

References

1. Cerner Multum, Inc. "Australian Product Information."

2. (2009) "Product Information. Twynsta (amlodipine-telmisartan)." Boehringer-Ingelheim

Further information

Amlodipine/telmisartan side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.