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Uceris (rectal)

Generic Name: budesonide (rectal) (bue DES oh nide)
Brand Name: Uceris

What is budesonide rectal?

Budesonide is a steroid that reduces inflammation in the body.

Budesonide rectal is used to treat ulcerative colitis.

Budesonide rectal may also be used for purposes not listed in this medication guide.

What is the most important information I should know about budesonide rectal?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before using budesonide rectal?

You should not use this medicine if you are allergic to budesonide.

To make sure budesonide is safe for you, tell your doctor if you have:

  • tuberculosis (now or in the past);

  • a serious bacterial, viral, or fungal infection;

  • herpes infection of the eyes;

  • cirrhosis or other liver disease;

  • diabetes;

  • high blood pressure;

  • osteoporosis;

  • a stomach ulcer;

  • glaucoma;

  • a weak immune system (caused by disease or by using certain medicines); or

  • if you plan to have surgery.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Budesonide can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Budesonide rectal is not approved for use by anyone younger than 18 years old.

How should I use budesonide rectal?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not take budesonide rectal by mouth. It is for use only in your rectum.

Budesonide rectal is usually given once in the morning and once in the evening for 2 weeks. Then you will use the medicine only once per day (at bedtime) for 4 more weeks. Follow your doctor's dosing instructions very carefully.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Try to empty your bowel and bladder just before using the rectal foam.

Wash your hands before and after using this medicine.

Warm the medicine canister in your hands and shake it for 10 to 15 minutes before each use.

After using budesonide rectal at bedtime, avoid using the bathroom until the next morning.

Budesonide rectal foam is flammable. Do not use near high heat or open flame, or while smoking.

If you plan to have a colonoscopy, tell your doctor ahead of time. You may need to stop using budesonide rectal while you are using laxative medicine to prepare for the colonoscopy. Follow your doctor's instructions about when to start using budesonide rectal foam again.

If you also use another steroid medication, do not stop using it suddenly or you may have unpleasant withdrawal symptoms. Talk with your doctor about tapering your steroid dose before stopping completely.

Store at room temperature away from moisture and heat.

Keep the medicine canister away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty rectal foam canister.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of budesonide rectal is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using budesonide rectal?

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medicine.

Grapefruit and grapefruit juice may interact with budesonide and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.

Budesonide rectal side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • signs of infection--fever, chills, body aches, vomiting, flu symptoms; or

  • signs of low adrenal gland hormones--worsening tiredness or muscle weakness, feeling light-headed, nausea, vomiting, loss of appetite, diarrhea, and weight loss.

Common side effects may include:

  • nausea; or

  • low adrenal gland hormones.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect budesonide rectal?

Other drugs may interact with budesonide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about budesonide rectal.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 1.01.

Date modified: October 14, 2016
Last reviewed: May 23, 2016