Generic Name: triptorelin (TRIP toe REL in)
Brand Name: Trelstar, Triptodur, Trelstar Depot, Trelstar LA, Trelstar LA Mixject, Trelstar Depot Mixject, Trelstar Mixject
What is triptorelin?
Triptorelin is a man-made form of a hormone that regulates many processes in the body.
The Triptodur brand of triptorelin is used to treat precocious puberty in boys and girls who are at least 2 years old.
Triptorelin may also be used for purposes not listed in this medication guide.
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Some people using triptorelin have had new or worsening mental problems or seizures (convulsions). Call your doctor right away if you have a seizure, or any unusual changes in mood or behavior (anger, aggression, crying, feeling restless or irritable).
Triptorelin can cause a temporary increase in certain hormones, especially when you first start using triptorelin. This may cause side effects that are similar to the condition being treated.
Before taking this medicine
Do not use triptorelin if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine.
Tell your doctor if you have ever had:
heart disease, long QT syndrome or other heart rhythm disorder;
a heart attack or stroke;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
epilepsy or other seizure disorder;
mental illness; or
a tumor or blood vessel problem in your brain.
You should not breast-feed while using this medicine.
This medicine may affect fertility (ability to have children) in men.
How should I use triptorelin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Triptorelin is injected into a muscle. A healthcare provider can teach you how to properly use the medication by yourself.
Triptorelin is usually given once every 4, 12, or 24 weeks. Your dose schedule will depend on the strength and brand of triptorelin you are using.
Triptorelin must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.
Triptorelin can increase certain hormones when you first start using triptorelin or after each new injection. This may cause symptoms of prostate cancer or precocious puberty to get worse for a short time. These side effects should get better within 1 to 2 months. Call your doctor if your symptoms do not improve, or if they get worse while using triptorelin.
You may need frequent medical tests.
Store at room temperature away from moisture and heat. Do not freeze.
Each vial (bottle) is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose, or if you miss an appointment for your triptorelin injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using triptorelin?
triptorelin can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Triptorelin side effects
Get emergency medical help if you have signs of an allergic reaction: hives, red skin rash, severe itching, sweating; dizziness, fast heartbeats; trouble breathing or swallowing; swelling of your face, lips, tongue, or throat.
Triptorelin can cause a temporary increase in certain hormones, especially when you first start using this medicine. This may cause side effects that are similar to the condition being treated. Call your doctor at once if you have:
painful or difficult urination, burning when you urinate, blood in the urine;
(in children) new or worsening signs of puberty;
chest pain or pressure, pain spreading to your jaw or shoulder;
sudden numbness or weakness, slurred speech;
loss of movement in any part of your body;
high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor; or
nerve problems--back pain, muscle weakness, problems with balance or coordination, severe numbness or tingling in your legs or feet, loss of bladder or bowel control.
Common side effects may include:
pain, swelling, itching, or redness where an injection was given;
decreased interest in sex, impotence, trouble having an orgasm;
headache, bone pain, pain or swelling in your legs;
vaginal bleeding; or
cold or flu symptoms (stuffy nose, sneezing, cough, sore throat, ear pain).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Triptorelin dosing information
Usual Adult Dose for Prostate Cancer:
Due to different release characteristics, the dosage strengths are not additive and must be selected based upon the desired dosing schedule.
3.75 mg intramuscularly (IM) every 4 weeks
11.25 mg IM every 12 weeks
22.5 mg IM every 24 weeks
Comments: Administered as a single intramuscular injection in either buttock.
Use: Palliative treatment of advanced prostate cancer
What other drugs will affect triptorelin?
Other drugs may affect triptorelin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 10.01.
More about triptorelin
- Triptorelin Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 5 Reviews
- Drug class: gonadotropin releasing hormones