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Triptorelin Dosage

Applies to the following strength(s): 11.25 mg/3 months ; 3.75 mg/month ; 22.5 mg/6 months

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Prostate Cancer

Due to different release characteristics, the dosage strengths are not additive and must be selected based upon the desired dosing schedule.

3.75 mg intramuscularly (IM) every 4 weeks
or
11.25 mg IM every 12 weeks
or
22.5 mg IM every 24 weeks

Comments: Administered as a single intramuscular injection in either buttock.

Use: Palliative treatment of advanced prostate cancer

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Must be administered under the supervision of a physician.
-Alternate injection site periodically.

Storage requirements:
-Store at room temperature, do not freeze

Reconstitution/preparation techniques:
-Reconstitute in sterile water only; do not use any other diluent.
-Administer immediately after reconstitution.
-The manufacturer product information should be consulted.

Patient advice:
-Patients are likely to have an increase in testosterone after the first dose, which may worsen their symptoms during the first weeks of treatment.
-The increased testosterone and symptoms should decline after 3 to 4 weeks.
-Advise patients that there is an increased risk of developing diabetes, myocardial infarction, sudden cardiac death, and stroke.
-Advise patients that allergic reactions may occur, and serious reactions require immediate treatment.

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