Skip to Content


Generic Name: glycopyrrolate (oral) (GLY koe PIE roe late)
Brand Name: Cuvposa, Robinul, Robinul Forte

Medically reviewed by on Sep 6, 2017 – Written by Cerner Multum

What is Robinul?

Robinul reduces the secretions of certain organs in the body.

Robinul helps to control conditions such as peptic ulcers that involve excessive stomach acid production.

Robinul is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

Robinul may also be used for purposes not listed in this medication guide.

Important Information

You should not use Robinul if you have urination problems, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, or myasthenia gravis.

Before taking this medicine

You should not use Robinul if you are allergic to it, or if you have:

  • a bladder obstruction or other urination problems;

  • a blockage in your digestive tract (stomach or intestines), severe constipation;

  • severe ulcerative colitis or toxic megacolon;

  • eye problems;

  • glaucoma; or

  • myasthenia gravis.

To make sure Robinul is safe for you, tell your doctor if you have ever had:

It is not known whether Robinul will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether glycopyrrolate passes into breast milk or if it could affect the nursing baby. This medicine can slow breast milk production. Tell your doctor if you are breast-feeding.

Do not give Robinul to a child without medical advice.

How should I take Robinul?

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may need to take Robinul on an empty stomach, at least 1 hour before or 2 hours after a meal. Follow the instructions provided with your medicine.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe muscle weakness, dilated pupils, jerky muscle movements, or seizure (convulsions).

What should I avoid while taking Robinul?

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol with Robinul can cause side effects.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Robinul can decrease sweating and you may be more prone to heat stroke.

Robinul side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Robinul and call your doctor at once if you have:

  • severe constipation, severe stomach pain and bloating;

  • diarrhea (especially if you have a colostomy or ileostomy);

  • painful or difficult urination;

  • fast or pounding heartbeats, fluttering in your chest;

  • confusion, severe drowsiness;

  • fever, shallow breathing, weak pulse, hot and red skin; or

  • (in a child taking Robinul) dry diapers, fussiness, or excessive crying.

Common side effects may include:

  • constipation, nausea, vomiting, bloating;

  • drowsiness, dizziness, weakness;

  • sleep problems (insomnia);

  • blurred vision;

  • dry mouth, stuffy nose;

  • decreased sweating;

  • flushing (warmth, redness, or tingly feeling);

  • headache; or

  • rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Robinul?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may interact with glycopyrrolate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.