Robinul Side Effects

Generic name: glycopyrrolate

Medically reviewed by Drugs.com. Last updated on May 14, 2025.

Note: This document provides detailed information about Robinul Side Effects associated with glycopyrrolate. Some dosage forms listed on this page may not apply specifically to the brand name Robinul.

Applies to glycopyrrolate: oral solution, oral tablet, oral tablet disintegrating.

Other dosage forms:

• inhalation solution
• solution

Precautions

It is very important that your doctor or your child's doctor check your progress at regular visits. This will allow your doctor to make sure that this medicine is working properly and to check for unwanted effects.

You should not take potassium chloride tablets or other potassium supplements (in tablet or capsule forms) while using this medicine. Using these medicines together may cause delayed movement of the potassium supplement through the esophagus and stomach.

This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Check with your doctor if you or your child has constipation, diarrhea, stomach distention (swelling), pain, nausea, or vomiting.

Check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has irritability, crying, decrease in the frequency of urine, or difficult or painful urination.

If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, check with your doctor as soon as possible.

This medicine may make you or your child sweat less, causing your body temperature to increase. Use extra care to avoid becoming overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.

This medicine may make you or your child dizzy, confused, drowsy, or less alert than you are normally. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Robinul

Along with its needed effects, glycopyrrolate (the active ingredient contained in Robinul) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking glycopyrrolate:

Get emergency help immediately if any of the following symptoms of overdose occur while taking glycopyrrolate:

• blurred vision
• confusion
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• muscle weakness
• sweating
• trouble breathing
• unusual tiredness or weakness

Other side effects of Robinul

Some side effects of glycopyrrolate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

See also:

For healthcare professionals

Applies to glycopyrrolate: compounding powder, inhalation capsule, inhalation solution, injectable solution, intravenous solution, oral solution, oral tablet, oral tablet disintegrating.

Gastrointestinal adverse events

• Very common (10% or more): Dry mouth (40%), vomiting (40%), constipation (35%)
• Frequency not reported: Abdominal distension, abdominal pain, stomach discomfort, chapped lips, flatulence, retching, dry tongue^[Ref]

Cardiovascular

• Very common (10% or more): Flushing (30%)
• Frequency not reported: Heart rate increase, pallor^[Ref]

Nervous system

• Very common (10% or more): Headache (15%)
• Frequency not reported: Convulsion, dysgeusia, nystagmus
• Postmarketing reports: Loss of taste^[Ref]

Genitourinary

• Very common (10% or more): Urinary retention (15%)
• Postmarketing reports: Suppression of lactation^[Ref]

Immunologic

• Very common (10% or more): Sinusitis (15%), upper respiratory tract infection (15%)
• Frequency not reported: Pneumonia, tracheostomy infection, urinary tract infection^[Ref]

Respiratory

• Very common (10% or more): Nasal congestion (30%)
• Frequency not reported: Increased viscosity of bronchial secretion, nasal dryness^[Ref]

Psychiatric

• Frequency not reported: Irritability, agitation, restlessness, abnormal behavior, aggression, crying, impulse control disorder, moaning, mood altered^[Ref]

Dermatologic

• Frequency not reported: Dry skin, pruritus, rash^[Ref]

Metabolic

• Frequency not reported: Dehydration^[Ref]

Other

• Frequency not reported: Pain^[Ref]

Further information

Robinul side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer