Generic Name: glycopyrrolate (oral) (GLY koe PIE roe late)
Brand Names: Cuvposa, Robinul, Robinul Forte
Medically reviewed on October 13, 2017.
What is Cuvposa?
Cuvposa (glycopyrrolate) reduces the secretions of certain organs in the body.
Cuvposa is used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.
Cuvposa may also be used for purposes not listed in this medication guide.
You should not use Cuvposa if you have urination problems, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, or myasthenia gravis.
Before you take Cuvposa, tell your doctor if you have kidney disease, heart disease, a heart rhythm disorder, a stomach disorder, a colostomy or ileostomy, a thyroid disorder, high blood pressure, vision problems, or numbness and tingling.
Take Cuvposa on an empty stomach, at least 1 hour before or 2 hours after a meal. This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of Cuvposa, such as dizziness and drowsiness. Avoid becoming overheated or dehydrated during exercise and in hot weather. Cuvposa can decrease sweating and you may be more prone to heat stroke.
Before taking this medicine
You should not use Cuvposa if you are allergic to glycopyrrolate, or if you have:
a bladder obstruction or other urination problems;
a blockage in your digestive tract (stomach or intestines), severe constipation;
severe ulcerative colitis or toxic megacolon;
To make sure Cuvposa is safe for you, tell your doctor if you have ever had:
liver or kidney disease;
heart disease, a heart rhythm disorder;
high blood pressure;
a stomach disorder such as hiatal hernia, reflux disease, or slow digestion;
a colostomy or ileostomy;
a thyroid disorder; or
a nerve disorder.
It is not known whether Cuvposa will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether glycopyrrolate passes into breast milk or if it could affect the nursing baby. This medicine can slow breast milk production. Tell your doctor if you are breast-feeding.
Do not give Cuvposa to a child without medical advice.
How should I take Cuvposa?
Take Cuvposa exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.
You may need to take Cuvposa on an empty stomach, at least 1 hour before or 2 hours after a meal. Follow the instructions provided with your medicine.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Store at room temperature away from moisture and heat.
Cuvposa dosing information
Usual Pediatric Dose for Excessive Salivation:
3 years to 16 years with neurologic conditions associated with problem drooling:
Initiate dosing at 0.02 mg/kg orally three times daily and titrate in increments of 0.02 mg/kg every 5 to 7 days, based on therapeutic response and adverse reactions. Maximum recommended dose is 0.1 mg/kg three times daily, not to exceed 1.5 to 3 mg per dose based upon weight. Administer at least one hour before or two hours after meals.
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe muscle weakness, dilated pupils, jerky muscle movements, or seizure (convulsions).
What should I avoid while taking Cuvposa?
This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Drinking alcohol with this medicine can cause side effects.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Glycopyrrolate can decrease sweating and you may be more prone to heat stroke.
Cuvposa side effects
Get emergency medical help if you have signs of an allergic reaction to Cuvposa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Cuvposa and call your doctor at once if you have:
severe constipation, severe stomach pain and bloating;
diarrhea (especially if you have a colostomy or ileostomy);
painful or difficult urination;
fast or pounding heartbeats, fluttering in your chest;
confusion, severe drowsiness;
fever, shallow breathing, weak pulse, hot and red skin; or
(in a child taking glycopyrrolate) dry diapers, fussiness, or excessive crying.
Common Cuvposa side effects may include:
constipation, nausea, vomiting, bloating;
drowsiness, dizziness, weakness;
sleep problems (insomnia);
dry mouth, stuffy nose;
flushing (warmth, redness, or tingly feeling);
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Cuvposa?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Other drugs may interact with glycopyrrolate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Cuvposa only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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