Generic Name: oxycodone (ox i KOE done)
Brand Name: Oxaydo, OxyCONTIN, Oxyfast, Roxicodone, Xtampza ER
What is oxycodone?
Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic. Oxycodone is used to treat moderate to severe pain.
The extended-release form of this medicine is for around-the-clock treatment of pain. This form of oxycodone is not for use on an as-needed basis for pain.
Oxycodone may also be used for purposes not listed in this medication guide.
What is the most important information I should know about oxycodone?
You should not use oxycodone if you have severe asthma or breathing problems, or a blockage in your stomach or intestines.
Oxycodone can slow or stop your breathing, and may be habit-forming. Use only your prescribed dose, and swallow the pill whole to avoid a potentially fatal dose. Never share oxycodone with another person.
MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Oxycodone may cause life-threatening withdrawal symptoms in a newborn if the mother has taken this medicine during pregnancy.
Do not drink alcohol. Dangerous side effects or death could occur.
What should I discuss with my healthcare provider before using oxycodone?
You should not use oxycodone if you are allergic to it, or if you have:
severe asthma or breathing problems;
a blockage in your stomach or intestines; or
an allergy to any narcotic pain medicine (such as methadone, morphine, Percocet, Vicodin, Lortab, and many others), or narcotic cough medicine that contains codeine, hydrocodone, or dihydrocodeine.
You should not use oxycodone unless you are already using a similar opioid medicine and are tolerant to it. Ask your doctor if you are not sure you are opioid-tolerant.
Some medicines can interact with oxycodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
To make sure oxycodone is safe for you, tell your doctor if you have:
any type of breathing problem or lung disease;
a history of head injury, brain tumor, or seizures;
a history of drug abuse, alcohol addiction, or mental illness;
liver or kidney disease;
Addison's disease or other adrenal gland disorder;
problems with your gallbladder, pancreas, or thyroid; or
if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).
If you use oxycodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.
Oxycodone can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using oxycodone.
Do not give this medicine to a child without medical advice.
How should I use oxycodone?
Follow all directions on your prescription label. Oxycodone can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take oxycodone in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Oxycodone may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away oxycodone is against the law.
Stop taking all other around-the-clock narcotic pain medicines when you start taking extended-release oxycodone (Oxycontin).
Take oxycodone with food.
Do not crush, break, or open an extended-release tablet. Swallow it whole to avoid exposure to a potentially fatal dose.
If your doctor has told you to take two or more oxycodone tablets per dose, take the tablets one at a time. Drink plenty of water to make swallowing easier and to prevent choking.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not stop using oxycodone suddenly after long-term use. Ask your doctor how to safely stop using this medicine.
Never crush or break an oxycodone pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death with the misuse of oxycodone and similar prescription drugs.
Store at room temperature, away from heat, moisture, and light.
Always check your bottle to make sure you have received the correct pills (same brand and type) of medicine prescribed by your doctor.
Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Do not keep leftover oxycodone pills or liquid. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush any unused pills or liquid medicine down the toilet.
What happens if I miss a dose?
Since oxycodone is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A oxycodone overdose can be fatal, especially in a child or other person using the medicine without a prescription.
What should I avoid while using oxycodone?
Do not drink alcohol. Dangerous side effects or death could occur.
This medicine may impair your thinking or reactions. Avoid driving or operating machinery until you know how oxycodone will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Grapefruit and grapefruit juice may interact with oxycodone and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
Oxycodone side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Like other narcotic medicines, oxycodone can slow your breathing. Death may occur if breathing becomes too weak.
Call your doctor at once if you have:
shallow breathing, slow heartbeat, cold, clammy skin;
confusion, severe drowsiness;
infertility, missed menstrual periods;
impotence, sexual problems, loss of interest in sex;
a light-headed feeling, like you might pass out; or
low cortisol levels--nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Oxycodone is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Common side effects may include:
drowsiness, headache, dizziness, tired feeling;
stomach pain, nausea, vomiting, constipation, loss of appetite;
dry mouth; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect oxycodone?
Some drugs can raise or lower your blood levels of oxycodone, which may cause side effects or make oxycodone less effective. Tell your doctor if you also use certain antibiotics, antifungal medications, heart or blood pressure medications, or medicines to treat HIV or AIDS.
Narcotic (opioid) medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:
other narcotic medications--opioid pain medicine or prescription cough medicine;
drugs that make you sleepy or slow your breathing--a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine; or
drugs that affect serotonin levels in your body--medicine for depression, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting.
This list is not complete. Other drugs may interact with oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about OxyContin (oxycodone)
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about oxycodone.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 10.11.
Date modified: November 30, 2016
Last reviewed: October 14, 2016