Medically reviewed: November 2, 2017
What is minocycline?
Minocycline may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
If you are using minocycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.
To make sure minocycline is safe for you, tell your doctor if you have:
You should not use minocycline if you are pregnant. It could harm the unborn baby or cause permanent tooth discoloration later in life. Use effective birth control to prevent pregnancy while you are using this medicine, whether you are a man or a woman.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is taking minocycline. The use of this medicine by either parent may cause tooth discoloration later in the baby's life.
Minocycline passes into breast milk and may affect bone and tooth development in a nursing baby. You should not breast-feed while you are taking minocycline.
Do not give this medicine to a child without medical advice. Minocycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old.
How should I take minocycline?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take this medicine with a full glass of water.
You may take minocycline with or without food.
Do not crush, chew, or break an extended-release capsule or tablet. Swallow it whole.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Minocycline will not treat a viral infection such as the flu or a common cold.
If you use this medicine long-term, you may need frequent medical tests. You may also need to stop taking minocycline for a short time if you need surgery.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using minocycline.
Store at room temperature away from moisture, heat, and light.
Throw away any minocycline not used before the expiration date on the medicine label. Using expired minocycline can cause damage to your kidneys.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking minocycline?
For 2 hours before or after you take minocycline: Avoid taking antacids, laxatives, multivitamins, or supplements that contain calcium, magnesium, or iron. These other medicines can make it harder for your body to absorb minocycline.
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Avoid exposure to sunlight or tanning beds. Minocycline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Minocycline side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This may be more likely with long-term use of minocycline, and the reaction may occur several weeks after you began using this medicine.
Call your doctor at once if you have:
kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, loss of appetite, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes);
lupus-like syndrome (with long-term use of minocycline to treat acne)--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color;
increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, vision problems, pain behind your eyes; or
signs of inflammation in your body--swollen glands, flu symptoms, easy bruising or bleeding, severe tingling or numbness, muscle weakness, chest pain, new or worsening cough with fever, trouble breathing.
Common side effects may include:
nausea, diarrhea, loss of appetite;
dizziness, spinning sensation;
headache, feeling tired;
swollen tongue, cough, trouble swallowing;
muscle or joint pain;
rash, itching; or
discoloration of you skin or nails.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect minocycline?
Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with minocycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 14.01.
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