Medically reviewed on April 2, 2018
What is Aspir 81?
Aspir 81 is a salicylate (sa-LIS-il-ate). It works by reducing substances in the body that cause pain, fever, and inflammation.
Aspir 81 is used to treat pain, and reduce fever or inflammation. This medicine is sometimes used to treat or prevent heart attacks, strokes, and chest pain (angina). This medicine should be used for cardiovascular conditions only under the supervision of a doctor.
Aspir 81 may also be used for purposes not listed in this medication guide.
You should not use Aspir 81 if you have a bleeding disorder such as hemophilia, a recent history of stomach or intestinal bleeding, or if you are allergic to an NSAID (non-steroidal anti-inflammatory drug).
Aspir 81 can cause Reye's syndrome, a serious and sometimes fatal condition in children.
Before taking this medicine
Do not give Aspir 81 to a child or teenager with a fever, flu symptoms, or chicken pox. Aspir 81 can cause Reye's syndrome, a serious and sometimes fatal condition in children.
You should not use Aspir 81 if you are allergic to it, or if you have:
a recent history of stomach or intestinal bleeding;
a bleeding disorder such as hemophilia; or
if you have ever had an asthma attack or severe allergic reaction after taking Aspir 81 or an NSAID (non-steroidal anti-inflammatory drug).
Tell your doctor if you have ever had:
asthma or seasonal allergies;
a bleeding or blood clotting disorder;
Taking Aspir 81 during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breast-feed while using this medicine.
How should I take Aspir 81?
Use exactly as directed on the label, or as prescribed by your doctor.
Take with food if Aspir 81 upsets your stomach.
Do not crush, chew, break, or open an enteric-coated or delayed-release pill. Swallow it whole.
The chewable tablet form of aspirin must be chewed before swallowing.
If you use the orally disintegrating tablet or the dispersible tablet, follow all dosing instructions provided with your medicine.
If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.
Do not take this medicine if you smell a strong vinegar odor in the Aspir 81 bottle. The medicine may no longer be effective.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Since Aspir 81 is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include temporary hearing loss, seizure (convulsions), or coma.
What should I avoid while taking Aspir 81?
Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding.
If you are taking Aspir 81 to prevent heart attack or stroke, avoid also taking ibuprofen (Advil, Motrin). Ibuprofen may make this medicine less effective. If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the this medicine (non-enteric coated form).
Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to Aspir 81 (such as magnesium salicylate, ibuprofen, ketoprofen, or naproxen).
Aspir 81 side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Aspir 81 and call your doctor at once if you have:
ringing in your ears, confusion, hallucinations, rapid breathing, seizure (convulsions);
bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
fever lasting longer than 3 days; or
swelling, or pain lasting longer than 10 days.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Aspir 81?
Ask your doctor before using Aspir 81 if you take an antidepressant. Taking certain antidepressants with this medicine may cause you to bruise or bleed easily.
Ask a doctor or pharmacist before using Aspir 81 with any other medications, especially:
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 15.02.
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