Generic name: fexofenadine [ FEX-oh-FEN-a-deen ]
Brand names: Allegra 12 Hour Allergy, Allegra 24 Hour Allergy, Allegra Allergy, Allegra OTC, Aller-Ease, ... show all 8 brands Allergy Relief (Fexofenadine HCl), Children's Allegra Allergy, Children's Allegra ODT
Drug class: Antihistamines

Medically reviewed by Drugs.com on Jan 20, 2023. Written by Cerner Multum.

What is Allergy Relief (Fexofenadine HCl)?

Allergy Relief (Fexofenadine HCl) is an antihistamine that is used to treat the symptoms of seasonal allergies (hay fever) in adults and children.

Allergy Relief (Fexofenadine HCl) is also used to treat skin itching and hives caused by a condition called chronic idiopathic urticaria in adults and children at least 6 years old.

There are many brands and forms of Allergy Relief (Fexofenadine HCl) available. Not all brands are listed on this leaflet.

Allergy Relief (Fexofenadine HCl) may also be used for purposes not listed in this medication guide.

Allergy Relief (Fexofenadine HCl) side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Allergy Relief (Fexofenadine HCl) and call your doctor at once if you have:

• flu-like symptoms (fever, chills, unusual tiredness);

• new or worsening cough;

• pain; or

• signs of an ear infection--fever, ear pain or full feeling, trouble hearing, drainage from the ear, fussiness in a child.

Common side effects of Allergy Relief (Fexofenadine HCl) may include:

• headache;

• back pain; or

• cold symptoms such as stuffy nose, sinus pain, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Do not take Allergy Relief (Fexofenadine HCl) with fruit juice (such as apple, orange, or grapefruit).

Before taking this medicine

You should not use Allergy Relief (Fexofenadine HCl) if you are allergic to it.

Ask a doctor or pharmacist if Allergy Relief (Allergy Relief (Fexofenadine HCl) HCl) is safe to use if you have:

• kidney disease.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Older adults may be more sensitive to the effects of this medicine. If you are 65 or older, ask a doctor before taking Allergy Relief (Fexofenadine HCl).

This medicine may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

How should I take Allergy Relief (Fexofenadine HCl)?

Use exactly as directed on the label, or as prescribed by your doctor.

Always follow directions on the medicine label about giving cough or cold medicine to a child.

• Ask a doctor before giving Allergy Relief (Allergy Relief (Fexofenadine HCl) HCl) liquid to a child younger than 2 years old.

• The disintegrating (melting) tablets are not for use in a child younger than 6 years old.

• The 12-hour and 24-hour forms of Allergy Relief (Allergy Relief (Fexofenadine HCl) HCl) are not for use in a child younger than 12 years old.

Take this medicine only with water.

Take the disintegrating tablet on an empty stomach.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing cup provided, or use a medicine dose-measuring device (not a kitchen spoon).

Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.

Call your doctor if your symptoms do not improve, or if they get worse.

Store Allergy Relief (Fexofenadine HCl) in its original package at room temperature, away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Allergy Relief (Allergy Relief (Fexofenadine HCl) HCl) is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dry mouth, dizziness, or drowsiness.

What should I avoid while taking Allergy Relief (Fexofenadine HCl)?

Do not take Allergy Relief (Fexofenadine HCl) with fruit juice (such as apple, orange, or grapefruit). These juices can make it harder for your body to absorb Allergy Relief (Fexofenadine HCl).

Avoid taking an antacid within 2 hours before or after you take Allergy Relief (Fexofenadine HCl). Allergy Relief (Fexofenadine HCl) should not be used at the same time as antacids that contain magnesium or aluminum.

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

What other drugs will affect Allergy Relief (Fexofenadine HCl)?

Using Allergy Relief (Fexofenadine HCl) with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Ask a doctor or pharmacist before using Allergy Relief (Fexofenadine HCl) with any other medications, especially:

• ketoconazole; or

• erythromycin.

This list is not complete. Other drugs may affect Allergy Relief (Fexofenadine HCl), including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Related/similar drugs

prednisone, hydroxyzine, fluticasone nasal, cetirizine, loratadine, diphenhydramine, promethazine, Zyrtec, Xolair

Frequently asked questions

• What are the most common skin conditions? (with photos)

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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