Genvoya vs Stribild for HIV - How do they compare?
Genvoya and Stribild are both four-drug, antiviral combinations containing elvitegravir, cobicistat, emtricitabine, and tenofovir indicated as complete regimens for the treatment of HIV-1 infection.
The difference between Genvoya and Stribild is in the form of tenofovir contained in each product.
Genvoya contains a newer form of tenofovir called tenofovir alafenamide (TAF) and Stribild contains the original form of tenofovir as tenofovir disoproxil fumarate (TDF).
Tenofovir alafenamide is a prodrug of tenofovir that has been designed to enter HIV-infected cells more efficiently than TDF, and it can therefore be given at a much lower dose (less than one-tenth) than TDF. TAF appears to be associated with less kidney toxicity and decreases in bone density compared to TDF.
The dose for both Genvoya and Stribild is one tablet taken orally once daily with food.
| Genvoya | Stribild | |
|---|---|---|
| FDA Approved | November 5, 2015 | August 27, 2012 |
| How Supplied |
Each tablet contains:
|
Each tablet contains:
|
| Indication |
HIV-1 Infection
|
HIV-1 Infection
|
Genvoya and Stribild are both manufactured by Gilead Sciences Inc.
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Symtuza is a four-drug combination of darunavir (DRV), a human immunodeficiency virus (HIV-1) protease inhibitor, cobicistat (COBI), a CYP3A inhibitor, and emtricitabine (FTC) and tenofovir alafenamide (TAF). Continue reading
What is Genvoya used to treat?
Genvoya is an oral prescription medicine used to treat human immunodeficiency virus (HIV) in adults and children who are at least 12 years old and who weigh at least 55 pounds (25 kilograms). Continue reading
How long does Genvoya stay in your system?
Genvoya is a fixed-dose combination tablet used to treat human immunodeficiency virus (HIV) 1 infection. It contains four different drugs: cobicistat, elvitegravir, emtricitabine and tenofovir alafenamide.
To eliminate the active antiviral agents in Genvoya (elvitegravir, emtricitabine and tenofovir alafenamide) from your system takes up to 70.95 hours. Continue reading
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