Entresto and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Entresto (sacubitril / valsartan).
Moderate Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Moderate-to-high dietary intake of potassium, especially salt substitutes, may increase the risk of hyperkalemia in some patients who are using angiotensin II receptor blockers (ARBs). ARBs can promote hyperkalemia through inhibition of angiotensin II-induced aldosterone secretion. Patients with diabetes, heart failure, dehydration, or renal insufficiency have a greater risk of developing hyperkalemia.
MANAGEMENT: Patients should receive dietary counseling and be advised to not use potassium-containing salt substitutes or over-the-counter potassium supplements without consulting their physician. If salt substitutes are used concurrently, regular monitoring of serum potassium levels is recommended. Patients should also be advised to seek medical attention if they experience symptoms of hyperkalemia such as weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.
- "Product Information. Cozaar (losartan)." Merck & Company Inc (2001):
- "Product Information. Diovan (valsartan)." Novartis Pharmaceuticals (2001):
Entresto drug interactions
There are 282 drug interactions with Entresto (sacubitril / valsartan).
Entresto disease interactions
There are 8 disease interactions with Entresto (sacubitril / valsartan) which include:
- renal artery stenosis
- renal impairment
- renal/liver disease
More about Entresto (sacubitril / valsartan)
- Entresto consumer information
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- Pricing & coupons
- En español
- Drug class: angiotensin receptor blockers and neprilysin inhibitors
- FDA approval history
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|