Propofol and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with propofol.
Moderate Food Interaction
Alcohol can increase the nervous system side effects of propofol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with propofol. Do not use more than the recommended dose of propofol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, High plausibility
propofol - hyperlipidemia
Propofol is formulated in an oil-and-water emulsion and elevated triglycerides can occur during extended therapy. Propofol should be administered cautiously in patients with lipid disorders such as primary hyperlipoproteinemia, diabetic hyperlipemia, and pancreatitis. Each milliliter of propofol contains 0.1g of fat (1.1 kcal).
- "Product Information. Diprivan (propofol)." Astra-Zeneca Pharmaceuticals (2001):
- Mateu J, Barrachina F "Hypertriglyceridaemia associated with propofol sedation in critically ill patients." Intensive Care Med 22 (1996): 834-5
Propofol drug interactions
There are 338 drug interactions with propofol.
Propofol disease interactions
There are 5 disease interactions with propofol which include:
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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