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Arava and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Arava (leflunomide).


Leflunomide Food

Moderate Food Interaction

Leflunomide can be taken with or without food. It is important to take leflunomide regularly to get the most benefit. Discuss with your doctor the use of alcohol while taking leflunomide. Alcohol and leflunomide can both be damaging to the liver.

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Leflunomide High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

leflunomide - hypertension

Hypertension was reported as an adverse reaction in patients on leflunomide. Blood pressure should be monitored during treatment and periodically thereafter as this agent can increase the blood pressure in these patients.


  1. (2001) "Product Information. Arava (leflunomide)." Hoechst Marion Roussel

Arava drug interactions

There are 655 drug interactions with Arava (leflunomide).

Arava disease interactions

There are 7 disease interactions with Arava (leflunomide) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.