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Dobutrex (dobutamine) and Alcohol / Food Interactions

There is 1 alcohol/food/lifestyle interaction with Dobutrex (dobutamine):

Major

High Blood Pressure (Hypertension)

Severe Potential Hazard, Moderate plausibility

dobutamine/arbutamine - arrhythmias

Dobutamine and arbutamine produce stimulation of the beta receptors of the heart. The use of these agents has been associated with an increase in heart rate, ventricular ectopy, atrial fibrillation, hypertension, enhanced A-V conduction, and arrhythmias. Therapy with dobutamine or arbutamine should be administered cautiously in patients with cardiac conduction disorders.

References

  1. "Product Information. Dobutrex (dobutamine)." Lilly, Eli and Company, Indianapolis, IN.
  2. Bianchi C, Diaz R, Gonzales C, Beregovich J "Effects of dobutamine on atrioventricular conduction." Am Heart J 90 (1975): 474-8
  3. Cohen A, Chauvel C, Benhalima B, Blanchard B "Complication of dobutamine stress echocardiography." Lancet 345 (1995): 201-2
  4. Tisdale JE, Patel R, Webb CR, Borzak S, Zarowitz BJ "Electrophysiologic and proarrhythmic effects of intravenous inotropic agents." Prog Cardiovasc Dis 38 (1995): 167-80
  5. Kinder C, Chamberlain J, Kall J, Kopp D, Johnson M, Costanzo MR, Wilber D "Prognostic significance of sustained ventricular tachyarrhythmia occurring during dobutamine infusion." J Heart Lung Transplant 13 (1994): 1045-50
  6. Poldermans D, Fioretti PM, Boersma E, Forster T, Vanurk H, Cornel JH, Arnese M, Roelandt JRTC "Safety of dobutamine-atropine stress echocardiography in patients with suspected or proven coronary artery disease." Am J Cardiol 73 (1994): 456-9
  7. Baudhuin T, Marwick T, Melin J, Wijns W, D'Hondt AM, Detry JM "Diagnosis of coronary artery disease in elderly patients: safety and efficacy of dobutamine echocardiography." Eur Heart J 14 (1993): 799-803
  8. Previtali M, Lanzarini L, Fetiveau R, Poli A, Diotallevi P "Dobutamine-induced and spontaneous sustained ventricular tachycardia in recent myocardial infarction." Eur Heart J 17 (1996): 803-4
  9. Picano E, Mathias W, Pingitore A, Bigi R, Previtali M "Safety and tolerability of dobutamine-atropine stress echocardiography: a prospective, multicentre study." Lancet 344 (1994): 1190-2
  10. "Product Information. GenESA (arbutamine)." Gensia Inc, San Diego, CA.
View all 10 references

Dobutrex (dobutamine) drug Interactions

There are 260 drug interactions with Dobutrex (dobutamine)

Dobutrex (dobutamine) disease Interactions

There are 5 disease interactions with Dobutrex (dobutamine) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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