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Dobutamine Pregnancy and Breastfeeding Warnings

Dobutamine is also known as: Dobutrex

Dobutamine Pregnancy Warnings

Animal studies have revealed no evidence of impaired fertility, harm to the fetus, or teratogenic effects associated with dobutamine. There are no controlled data in human pregnancy. Dobutamine should be given during pregnancy when need has been clearly established. There is only one case report of the use of dobutamine during the second trimester in a 41-year-old woman who suffered an inferior wall myocardial infarction and cardiac arrest. The woman subsequently delivered at 38 weeks gestation. The female infant weight and head circumference were at the greater than 50th and greater than 10th percentile, respectively. Apgar scores were 6 and 8 at 1 and 5 minutes, respectively. No abnormality was discovered in the initial assessment. By age 17 months all normal landmarks were passed, but the weight and height were inexplicably below the 10th percentile. FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

FDA pregnancy category: B Potential benefit should outweigh the potential risk.

See references

Dobutamine Breastfeeding Warnings

Use dobutamine only if clearly needed. Excreted into human milk: Unknown Excreted into animal milk: Unknown The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Dobutrex (dobutamine)." Lilly, Eli and Company, Indianapolis, IN.
  2. Stokes IM, Evans J, Stone M "Myocardiol infarction and cardiac arrest in the second trimester followed by assisted vaginal delivery under epidural analgesia at 38 weeks gestation." Br J Obstet Gynaecol 91 (1984): 197-8

References for breastfeeding information

  1. "Product Information. Dobutrex (dobutamine)." Lilly, Eli and Company, Indianapolis, IN.

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