Zaleplon Drug Interactions
Currently displaying a list of 421 drugs known to interact with zaleplon.
- 28 major drug interactions
- 393 moderate drug interactions
Medications known to interact with zaleplon
Note: Showing generic names only.
A
- abametapir topical
- acebutolol
- acetylcarbromal
- acrivastine
- adagrasib
- aldesleukin
- alfentanil
- alfuzosin
- allopurinol
- alprazolam
- amiloride
- aminoglutethimide
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amyl nitrite
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprocitentan
- aripiprazole
- armodafinil
- asenapine
- atenolol
- azatadine
- azilsartan medoxomil
B
- baclofen
- belzutifan
- benazepril
- bendroflumethiazide
- benzthiazide
- benztropine
- bepridil
- berotralstat
- betaxolol
- bexarotene
- biperiden
- bisoprolol
- bosentan
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- candesartan
- cannabidiol
- cannabis
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carvedilol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- cimetidine
- citalopram
- clemastine
- clevidipine
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- conivaptan
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dabrafenib
- dantrolene
- daridorexant
- deferasirox
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- diazoxide
- difelikefalin
- diltiazem
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- doxazosin
- doxepin
- doxylamine
- dronabinol
- droperidol
- duloxetine
E
- echinacea
- efavirenz
- elafibranor
- elagolix
- enalapril
- enalaprilat
- encorafenib
- entacapone
- enzalutamide
- eplerenone
- eprosartan
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethosuximide
- ethotoin
- etravirine
- ezogabine
F
- felbamate
- felodipine
- fenfluramine
- fenoldopam
- fentanyl
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosinopril
- fosphenytoin
- fospropofol
- fostamatinib
- furosemide
G
- gabapentin
- gabapentin enacarbil
- ganaxolone
- glycerol phenylbutyrate
- griseofulvin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
H
- halazepam
- haloperidol
- heroin
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxyzine
I
- ifosfamide
- iloperidone
- imipramine
- indapamide
- iptacopan
- irbesartan
- isocarboxazid
- isosorbide dinitrate
- isosorbide mononitrate
- isradipine
- itraconazole
- ivosidenib
K
L
- labetalol
- landiolol
- larotrectinib
- lasmiditan
- lemborexant
- lenacapavir
- lesinurad
- levamlodipine
- levetiracetam
- levocetirizine
- levodopa
- levomethadyl acetate
- levorphanol
- lidocaine
- lisinopril
- lithium
- lofexidine
- lonafarnib
- lonapegsomatropin
- lorazepam
- lorlatinib
- losartan
- loxapine
- lumateperone
- lurasidone
M
- maprotiline
- mavacamten
- mavorixafor
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methocarbamol
- methohexital
- methsuximide
- methyclothiazide
- methyldopa
- metoclopramide
- metolazone
- metoprolol
- metreleptin
- metyrosine
- mibefradil
- midazolam
- mifepristone
- minoxidil
- mirtazapine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- moexipril
- molindone
- morphine
- morphine liposomal
N
- nabilone
- nadolol
- nafcillin
- nalbuphine
- nebivolol
- nefazodone
- nelfinavir
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nisoldipine
- nitroglycerin
- nitroprusside
- nortriptyline
O
- olanzapine
- oliceridine
- olmesartan
- olopatadine nasal
- olutasidenib
- omaveloxolone
- opicapone
- opium
- oritavancin
- orphenadrine
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
P
- pacritinib
- paliperidone
- papaverine
- paramethadione
- paroxetine
- penbutolol
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perindopril
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenobarbital
- phenoxybenzamine
- phensuximide
- phentolamine
- phenylbutazone
- phenytoin
- pimozide
- pindolol
- pirtobrutinib
- pitolisant
- polythiazide
- posaconazole
- pralsetinib
- pramipexole
- prazosin
- pregabalin
- primidone
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- propranolol
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ramipril
- rasagiline
- rauwolfia serpentina
- remifentanil
- remimazolam
- repotrectinib
- reserpine
- rifabutin
- rifampin
- rifapentine
- risperidone
- ropeginterferon alfa-2b
- ropinirole
- rotigotine
- rufinamide
S
- safinamide
- saquinavir
- scopolamine
- secobarbital
- selegiline
- sertraline
- sibutramine
- silodosin
- sirolimus
- sodium oxybate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotalol
- sotorasib
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sulfinpyrazone
- suvorexant
- suzetrigine
T
- tacrolimus
- tamsulosin
- tapentadol
- tasimelteon
- tazemetostat
- tecovirimat
- telithromycin
- telmisartan
- telotristat
- temazepam
- temsirolimus
- terazosin
- tetrabenazine
- thalidomide
- thioridazine
- thiothixene
- timolol
- tirzepatide
- tizanidine
- tolcapone
- torsemide
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- triamterene
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trofinetide
- troglitazone
- tucatinib
V
- vadadustat
- valbenazine
- valerian
- valproic acid
- valsartan
- vemurafenib
- venlafaxine
- verapamil
- vigabatrin
- vorasidenib
- voriconazole
Z
Zaleplon alcohol/food interactions
There is 1 alcohol/food interaction with zaleplon.
Zaleplon disease interactions
There are 8 disease interactions with zaleplon which include:
- alcohol intox
- depression
- drug dependence
- liver disease
- glaucoma
- liver disease
- resp depression
- renal dysfunction
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More about zaleplon
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- Reviews (134)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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