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Zaleplon Dosage

Applies to the following strength(s): 5 mg ; 10 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Geriatric Dose for:

Additional dosage information:

Usual Adult Dose for Insomnia

-Initial Dose: 10 mg orally immediately before bedtime or after going to bed and experiencing difficulty falling asleep.
-Maximum Dose: 20 mg

Use: Short-term treatment of insomnia.

Usual Geriatric Dose for Insomnia

-Initial Dose: 5 mg orally immediately before bedtime or after going to bed and experiencing difficulty falling asleep.
-Maximum Dose: 10 mg

Use: Short-term treatment of insomnia.

Renal Dose Adjustments

-Mild to Moderate Renal Impairment: No adjustment recommended.
-Severe Renal Impairment: Data not available.

Liver Dose Adjustments

-Mild to Moderate Hepatic Impairment: 5 mg orally immediately before bedtime or after going to bed and experiencing difficulty falling asleep.
-Severe Hepatic Impairment: Not recommended.

Dose Adjustments

Debilitated Patients and Low Weight Patients:
-Initial Dose: 5 mg orally immediately before bedtime or after going to bed and experiencing difficulty falling asleep.
-Maximum Dose: 10 mg

Concomitant Use with Cimetidine:
-Initial Dose: 5 mg orally immediately before bedtime or after going to bed and experiencing difficulty falling asleep.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV

Dialysis

Data not available.

Other Comments

Administration Advice:
-Avoid taking this drug with or immediately after a heavy, high-fat meal because the slower drug absorption would be expected to reduce the effect of this drug on sleep latency.

Storage Requirements:
-Store at room temperature and protect from light.

General:
-This drug has been shown to decrease the time to sleep onset, but it has not demonstrated ability to increase total sleep time or decrease the number of awakenings.
-Although there is no clinical experience with the use of flumazenil as an antidote for overdosage of this drug, it may be useful for that purpose based on data from animal studies.

Patient Advice:
-Avoid driving and other potentially dangerous activities such as operating machinery until you know how this drug affects you.
-Avoid alcohol while taking this drug.

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