Zaleplon Interactions
There are 421 drugs known to interact with zaleplon, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 28 are major, and 393 are moderate.
- View all 421 medications that may interact with zaleplon
- View zaleplon alcohol/food interactions (1)
- View zaleplon disease interactions (8)
Most frequently checked interactions
View interaction reports for zaleplon and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lunesta (eszopiclone)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Nexium (esomeprazole)
- ProAir HFA (albuterol)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Trintellix (vortioxetine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Zaleplon alcohol/food interactions
There is 1 alcohol/food interaction with zaleplon.
Zaleplon disease interactions
There are 8 disease interactions with zaleplon which include:
- alcohol intox
- depression
- drug dependence
- liver disease
- glaucoma
- liver disease
- resp depression
- renal dysfunction
Report options
More about zaleplon
- zaleplon consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (134)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Benadryl
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Ozempic
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Ambien
Ambien (zolpidem) is a prescription sedative used to treat insomnia, helping you fall asleep and ...
Lunesta
Lunesta is a sedative and is used to treat insomnia. Lunesta's effects typically begin within 30 ...
Eszopiclone
Eszopiclone (brand name Lunesta) is a sedative and is used to treat insomnia. Eszopiclone's effects ...
Temazepam
Temazepam is used to treat insomnia (trouble sleeping). Learn about side effects, interactions and ...
Doxepin
Doxepin systemic is used for anxiety, depression, insomnia, irritable bowel syndrome, major ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
