Zaleplon Interactions
There are 421 drugs known to interact with zaleplon, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 28 are major, and 393 are moderate.
- View all 421 medications that may interact with zaleplon
- View zaleplon alcohol/food interactions (1)
- View zaleplon disease interactions (8)
Most frequently checked interactions
View interaction reports for zaleplon and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lunesta (eszopiclone)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Nexium (esomeprazole)
- ProAir HFA (albuterol)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Trintellix (vortioxetine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Zaleplon alcohol/food interactions
There is 1 alcohol/food interaction with zaleplon.
Zaleplon disease interactions
There are 8 disease interactions with zaleplon which include:
- alcohol intox
- depression
- drug dependence
- liver disease
- glaucoma
- liver disease
- resp depression
- renal dysfunction
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More about zaleplon
- zaleplon consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (134)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
