Desyrel Drug Interactions
Currently displaying a list of 674 drugs known to interact with Desyrel (trazodone).
- 138 major drug interactions
- 521 moderate drug interactions
- 15 minor drug interactions
Medications known to interact with Desyrel
Note: Showing generic names only.
5
A
- abametapir topical
- abarelix
- abiraterone
- acebutolol
- acetylcarbromal
- acrivastine
- adagrasib
- adenosine
- albuterol
- aldesleukin
- alfentanil
- alfuzosin
- allopurinol
- almotriptan
- alprazolam
- amifampridine
- amiloride
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- amyl nitrite
- anagrelide
- anisindione
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- aprocitentan
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- asciminib
- asenapine
- astemizole
- atazanavir
- atenolol
- atomoxetine
- avacopan
- azatadine
- azelastine nasal
- azilsartan medoxomil
- azithromycin
B
- baclofen
- bedaquiline
- belzutifan
- benazepril
- bendroflumethiazide
- benoxinate ophthalmic
- benzgalantamine
- benzocaine topical
- benzthiazide
- benztropine
- bepridil
- berotralstat
- betaxolol
- bexarotene
- bicalutamide
- biperiden
- bisacodyl
- bisoprolol
- bitolterol
- boceprevir
- bosentan
- bosutinib
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- bumetanide
- bupivacaine
- bupivacaine liposome
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabozantinib
- candesartan
- cannabidiol
- cannabis
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carvedilol
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroprocaine
- chloroprocaine ophthalmic
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- cilostazol
- cinacalcet
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clemastine
- clevidipine
- clobazam
- clofazimine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobicistat
- cocaine nasal
- cocaine topical
- codeine
- conivaptan
- crizotinib
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dabrafenib
- dacomitinib
- dantrolene
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- degarelix
- delavirdine
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexfenfluramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- diazoxide
- dibucaine topical
- dicumarol
- difelikefalin
- digitoxin
- digoxin
- dihydroergotamine
- diltiazem
- dimenhydrinate
- diphenhydramine
- disopyramide
- divalproex sodium
- dofetilide
- dolasetron
- donepezil
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- duloxetine
- duvelisib
E
- echinacea
- efavirenz
- eletriptan
- eliglustat
- enalapril
- enalaprilat
- encorafenib
- entacapone
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- eprosartan
- ergotamine
- eribulin
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethosuximide
- ethotoin
- etidocaine
- etrasimod
- etravirine
- evening primrose
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenoldopam
- fentanyl
- fexinidazole
- fingolimod
- flavoxate
- flecainide
- flibanserin
- fluconazole
- fluoxetine
- fluphenazine
- flurazepam
- flutamide
- fluvoxamine
- formoterol
- fosamprenavir
- fosaprepitant
- foscarnet
- fosinopril
- fosphenytoin
- fostamatinib
- fostemsavir
- frovatriptan
- furazolidone
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- ginkgo
- givinostat
- givosiran
- glasdegib
- glycerin
- glycerol phenylbutyrate
- goserelin
- granisetron
- grepafloxacin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
H
- halazepam
- halofantrine
- haloperidol
- halothane
- heroin
- histrelin
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyzine
I
- ibutilide
- idarubicin
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indacaterol
- indapamide
- indinavir
- inotuzumab ozogamicin
- iobenguane I 123
- iohexol
- iomeprol
- iopamidol
- irbesartan
- isavuconazonium
- isocarboxazid
- isoetharine
- isoniazid
- isoproterenol
- isosorbide dinitrate
- isosorbide mononitrate
- isradipine
- itraconazole
- ivabradine
- ivosidenib
K
L
- labetalol
- lactitol
- lactulose
- lamotrigine
- landiolol
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- lemborexant
- lenacapavir
- lenvatinib
- letermovir
- leuprolide
- levalbuterol
- levamlodipine
- levetiracetam
- levobupivacaine
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- lidocaine ophthalmic
- lidocaine otic
- lidocaine topical
- lindane topical
- linezolid
- liothyronine
- liotrix
- lisdexamfetamine
- lisinopril
- lithium
- lofexidine
- lomefloxacin
- lonafarnib
- lonapegsomatropin
- loperamide
- lorazepam
- lorcaserin
- lorlatinib
- losartan
- loxapine
- lumateperone
- lurasidone
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- mavacamten
- mavorixafor
- meclizine
- mefloquine
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- mepivacaine
- meprobamate
- mesoridazine
- metaproterenol
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methsuximide
- methyclothiazide
- methyldopa
- methylene blue
- methysergide maleate
- metoclopramide
- metolazone
- metoprolol
- metrizamide
- metronidazole
- metyrosine
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- milnacipran
- mineral oil
- minoxidil
- mirabegron
- mirtazapine
- mitotane
- mobocertinib
- modafinil
- moexipril
- molindone
- morphine
- morphine liposomal
- moxifloxacin
N
- nabilone
- nadolol
- nalbuphine
- naratriptan
- nebivolol
- nefazodone
- nelfinavir
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nilutamide
- nimodipine
- nisoldipine
- nitroglycerin
- nitroprusside
- norfloxacin
- nortriptyline
O
- ofloxacin
- olanzapine
- oliceridine
- olmesartan
- olodaterol
- olopatadine nasal
- olutasidenib
- omaveloxolone
- omeprazole
- ondansetron
- opicapone
- opium
- oritavancin
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- oxytocin
- ozanimod
P
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- pasireotide
- pazopanib
- penbutolol
- pentamidine
- pentazocine
- pentobarbital
- perampanel
- perflutren
- pergolide
- perindopril
- perphenazine
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phenolphthalein
- phenoxybenzamine
- phensuximide
- phentolamine
- phenytoin
- pimavanserin
- pimozide
- pindolol
- pirbuterol
- pirtobrutinib
- pitolisant
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponesimod
- posaconazole
- pralsetinib
- pramipexole
- pramoxine topical
- prazosin
- pregabalin
- primaquine
- primidone
- probucol
- procainamide
- procaine
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- proparacaine ophthalmic
- propiomazine
- propofol
- propoxyphene
- propranolol
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ramipril
- ranolazine
- rasagiline
- rauwolfia serpentina
- relugolix
- remifentanil
- remimazolam
- repotrectinib
- reserpine
- revumenib
- ribociclib
- rifampin
- rifapentine
- rilpivirine
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rivastigmine
- rizatriptan
- rolapitant
- romidepsin
- ropinirole
- ropivacaine
- rotigotine
- rucaparib
- rufinamide
S
- safinamide
- salmeterol
- saquinavir
- scopolamine
- secobarbital
- selegiline
- selpercatinib
- senna
- sertraline
- sevoflurane
- sibutramine
- silodosin
- siponimod
- sirolimus
- sodium oxybate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotalol
- sotorasib
- sparfloxacin
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sulfamethoxazole
- sumatriptan
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus
- tamoxifen
- tamsulosin
- tapentadol
- tasimelteon
- tazemetostat
- tebentafusp
- tedizolid
- telaprevir
- telavancin
- telithromycin
- telmisartan
- telotristat
- temazepam
- temsirolimus
- terazosin
- terbinafine
- terbutaline
- terfenadine
- tetrabenazine
- tetracaine
- tetracaine ophthalmic
- tetracaine topical
- thalidomide
- thiethylperazine
- thioridazine
- thiothixene
- thyroid desiccated
- tiagabine
- timolol
- tizanidine
- tolcapone
- topiramate
- toremifene
- torsemide
- tramadol
- trandolapril
- tranylcypromine
- triamterene
- triazolam
- trichlormethiazide
- triclabendazole
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- triptorelin
- trofinetide
- troleandomycin
- tryptophan
- tucatinib
V
- vadadustat
- valbenazine
- valerian
- valproic acid
- valsartan
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- venlafaxine
- verapamil
- vigabatrin
- vilazodone
- voclosporin
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
Z
Desyrel alcohol/food interactions
There is 1 alcohol/food interaction with Desyrel (trazodone).
Desyrel disease interactions
There are 8 disease interactions with Desyrel (trazodone) which include:
- angle closure glaucoma
- mania
- seizures
- suicidality
- cardiovascular disease
- hyponatremia
- hypotension
- renal/liver disease
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More about Desyrel (trazodone)
- Desyrel consumer information
- Check interactions
- Compare alternatives
- Reviews (40)
- Drug images
- Latest FDA alerts (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: phenylpiperazine antidepressants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
