Eplerenone Drug Interactions
Currently displaying a list of 414 drugs known to interact with eplerenone.
- 76 major drug interactions
- 322 moderate drug interactions
- 16 minor drug interactions
Medications known to interact with eplerenone
Note: Showing generic names only.
A
- abametapir topical
- abiraterone
- acetylcarbromal
- adagrasib
- adalimumab
- alefacept
- alfentanil
- alprazolam
- amifostine
- amiloride
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- amprenavir
- anakinra
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- ardeparin
- aripiprazole
- armodafinil
- asciminib
- asenapine
- aspirin
- atazanavir
- avacopan
- avanafil
- azilsartan medoxomil
B
- baclofen
- belzutifan
- benazepril
- berotralstat
- betamethasone
- bexagliflozin
- bimekizumab
- boceprevir
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brodalumab
- bromfenac
- budesonide
- buprenorphine
- bupropion
- buspirone
- butorphanol
C
- cabergoline
- canagliflozin
- canakinumab
- candesartan
- cannabis
- captopril
- carbamazepine
- cariprazine
- carisoprodol
- celecoxib
- ceritinib
- chloral hydrate
- chloramphenicol
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpromazine
- chlorzoxazone
- choline salicylate
- ciprofloxacin
- citalopram
- clarithromycin
- clobazam
- clofazimine
- clomipramine
- clonazepam
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- codeine
- conivaptan
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- crizotinib
- cyclobenzaprine
- cyclosporine
D
- dabrafenib
- dalteparin
- danaparoid
- dapagliflozin
- daridorexant
- darunavir
- deferasirox
- deflazacort
- delavirdine
- demeclocycline
- desipramine
- desvenlafaxine
- dexamethasone
- dexmedetomidine
- dexmethylphenidate
- diazepam
- diclofenac
- diflunisal
- diltiazem
- dimenhydrinate
- diphenhydramine
- doxepin
- doxepin topical
- doxycycline
- dronabinol
- dronedarone
- drospirenone
- duloxetine
- duvelisib
E
- echinacea
- emapalumab
- empagliflozin
- enalapril
- enalaprilat
- encorafenib
- enoxaparin
- enzalutamide
- epoprostenol
- eprosartan
- eravacycline
- ertugliflozin
- erythromycin
- escitalopram
- ethanol
- ethchlorvynol
- etodolac
- etravirine
F
- fedratinib
- fenfluramine
- fenoprofen
- fentanyl
- fexinidazole
- finerenone
- fluconazole
- fludrocortisone
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosinopril
- fosphenytoin
- fostamatinib
- furazolidone
G
H
- halazepam
- haloperidol
- heparin
- heroin
- hydralazine
- hydrocodone
- hydrocortisone
- hydromorphone
- hydroxyzine
I
- ibuprofen
- idelalisib
- iloperidone
- iloprost
- imatinib
- imipramine
- indinavir
- indomethacin
- infliximab
- irbesartan
- isavuconazonium
- isocarboxazid
- itraconazole
- ivacaftor
K
L
- larotrectinib
- lazertinib
- lefamulin
- lenacapavir
- letermovir
- levodopa
- levoketoconazole
- levomilnacipran
- licorice
- linezolid
- lisinopril
- lithium
- lofexidine
- lonafarnib
- lonapegsomatropin
- lorazepam
- lorlatinib
- losartan
- loxapine
- lumateperone
- lurasidone
- lvp solution with potassium
M
- magnesium salicylate
- maprotiline
- maraviroc
- mavacamten
- mavorixafor
- meclofenamate
- mefenamic acid
- meloxicam
- meperidine
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methotrimeprazine
- methylphenidate
- methylprednisolone
- mibefradil
- miconazole
- midazolam
- mifepristone
- milnacipran
- minocycline
- mirtazapine
- mitotane
- modafinil
- moexipril
- molindone
- morphine
- morphine liposomal
N
- nabilone
- nabumetone
- nalbuphine
- naproxen
- nefazodone
- nelfinavir
- nemolizumab
- nevirapine
- nirogacestat
- nortriptyline
O
- olanzapine
- oliceridine
- olmesartan
- olutasidenib
- omadacycline
- omaveloxolone
- opium
- orphenadrine
- osilodrostat
- oxaprozin
- oxazepam
- oxycodone
- oxytetracycline
- ozanimod
P
- pacritinib
- paliperidone
- paraldehyde
- parenteral nutrition solution w/electrolytes
- paroxetine
- pentazocine
- pentosan polysulfate sodium
- pentoxifylline
- perindopril
- perphenazine
- phenelzine
- phenobarbital
- phenylbutazone
- phenytoin
- pimozide
- piroxicam
- pirtobrutinib
- pitolisant
- posaconazole
- potassium acetate
- potassium acid phosphate
- potassium aminobenzoate
- potassium bicarbonate
- potassium chloride
- potassium citrate
- potassium gluconate
- potassium guaiacolsulfonate
- potassium iodide
- potassium perchlorate
- potassium phosphate
- pralsetinib
- prednisolone
- prednisone
- primidone
- procarbazine
- prochlorperazine
- promazine
- promethazine
- propiomazine
- propoxyphene
- protriptyline
- pyrilamine
Q
R
- ramipril
- rasagiline
- remifentanil
- remimazolam
- repotrectinib
- ribociclib
- rifampin
- rifapentine
- rilonacept
- riociguat
- risperidone
- ritlecitinib
- ritonavir
- rofecoxib
- rufinamide
S
- safinamide
- salsalate
- saquinavir
- sarilumab
- satralizumab
- secobarbital
- secukinumab
- selegiline
- selexipag
- selpercatinib
- sertraline
- sibutramine
- sildenafil
- siltuximab
- sirolimus
- sodium nitrite
- sodium oxybate
- sodium salicylate
- sodium thiosalicylate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotagliflozin
- sotorasib
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sulindac
- suzetrigine
T
- tacrolimus
- tadalafil
- tarlatamab
- taurine
- teclistamab
- telaprevir
- telithromycin
- telmisartan
- telotristat
- temazepam
- temsirolimus
- tetrabenazine
- tetracycline
- thiethylperazine
- thioridazine
- thiothixene
- tigecycline
- tinzaparin
- tizanidine
- tocilizumab
- tolmetin
- tolvaptan
- trandolapril
- tranylcypromine
- trazodone
- treosulfan
- treprostinil
- triamcinolone
- triamterene
- triazolam
- trifluoperazine
- triflupromazine
- trimeprazine
- trimethoprim
- trimipramine
- trofinetide
- troleandomycin
- tucatinib
U
V
- vadadustat
- valdecoxib
- valsartan
- vamorolone
- vardenafil
- venlafaxine
- verapamil
- vericiguat
- vilazodone
- voclosporin
- vorasidenib
- voriconazole
- vortioxetine
- vosoritide
- voxelotor
Z
Eplerenone alcohol/food interactions
There are 2 alcohol/food interactions with eplerenone.
Eplerenone disease interactions
There are 4 disease interactions with eplerenone which include:
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
