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Calcium Carbonate / Simethicone Dosage

Applies to the following strengths: 500 mg-125 mg; 1000 mg-60 mg; 250 mg-62.5 mg; 400 mg-24 mg; 750 mg-80 mg; 1177 mg-80 mg; 500 mg-20 mg/5 mL; 400 mg-40 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Dyspepsia

Calcium carbonate 750 mg-simethicone 80 mg: 1 to 2 tablets orally up to 6 times a day as needed or as directed
-Maximum dose: Calcium carbonate 4500 mg-simethicone 480 mg (6 tablets)/day
-Duration of therapy: Up to 2 weeks

Calcium carbonate 1000 mg-simethicone 60 mg: 1 to 2 tablets orally up to 8 times a day as needed or as directed
-Maximum dose: Calcium carbonate 8000 mg-simethicone 480 mg (8 tablets)/day
-Duration of therapy: Up to 2 weeks

Comment: Patients should not use the maximum daily dose for longer than 2 weeks unless otherwise directed.

Uses:
-Relief of acid indigestion, heartburn, sour stomach, or upset stomach associated with these symptoms
-Relief of gas associated with acid indigestion, heartburn, or sour stomach
-Relief of bloating and pressure (gas)

Usual Adult Dose for Flatulence

Calcium carbonate 750 mg-simethicone 80 mg: 1 to 2 tablets orally up to 6 times a day as needed or as directed
-Maximum dose: Calcium carbonate 4500 mg-simethicone 480 mg (6 tablets)/day
-Duration of therapy: Up to 2 weeks

Calcium carbonate 1000 mg-simethicone 60 mg: 1 to 2 tablets orally up to 8 times a day as needed or as directed
-Maximum dose: Calcium carbonate 8000 mg-simethicone 480 mg (8 tablets)/day
-Duration of therapy: Up to 2 weeks

Comment: Patients should not use the maximum daily dose for longer than 2 weeks unless otherwise directed.

Uses:
-Relief of acid indigestion, heartburn, sour stomach, or upset stomach associated with these symptoms
-Relief of gas associated with acid indigestion, heartburn, or sour stomach
-Relief of bloating and pressure (gas)

Usual Pediatric Dose for Dyspepsia

Weight-based dosing:
Less than 10.9 kg: Data not available

10.9 to 21.4 kg:
Calcium carbonate 400 mg-simethicone 40 mg: 1 tablet orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 1200 mg-simethicone 120 mg (3 tablets)
-Duration of therapy: 2 weeks

21.8 to 43.2 kg:
Calcium carbonate 400 mg-simethicone 40 mg: 2 tablets orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 2400 mg-simethicone 240 mg
-Duration of therapy: 2 weeks

Age-based dosing:
Younger than 2 years: Data not available

2 to 5 years:
Calcium carbonate 400 mg-simethicone 40 mg: 1 tablet orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 1200 mg-simethicone 120 mg (3 tablets)
-Duration of therapy: 2 weeks

6 to 11 years:
Calcium carbonate 400 mg-simethicone 40 mg: 2 tablets orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 2400 mg-simethicone 240 mg (6 tablets)
-Duration of therapy: 2 weeks

12 years and older:
Calcium carbonate 750 mg-simethicone 80 mg: 1 to 2 tablets orally up to 6 times a day as needed or as directed
-Maximum dose: Calcium carbonate 4500 mg-simethicone 480 mg (6 tablets)/day
-Duration of therapy: Up to 2 weeks

Calcium carbonate 1000 mg-simethicone 60 mg: 1 to 2 tablets orally up to 8 times a day as needed or as directed
-Maximum dose: Calcium carbonate 8000 mg-simethicone 480 mg (8 tablets)/day
-Duration of therapy: Up to 2 weeks

Comment: Patients should not use the maximum daily dose for longer than 2 weeks unless otherwise directed.

Uses:
-Relief of acid indigestion, heartburn, sour stomach, or upset stomach associated with these symptoms
-Relief of gas associated with acid indigestion, heartburn, or sour stomach
-Relief of bloating and pressure (gas)
-Relief of overindulgence in food and drink

Usual Pediatric Dose for Flatulence

Weight-based dosing:
Less than 10.9 kg: Data not available

10.9 to 21.4 kg:
Calcium carbonate 400 mg-simethicone 40 mg: 1 tablet orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 1200 mg-simethicone 120 mg (3 tablets)
-Duration of therapy: 2 weeks

21.8 to 43.2 kg:
Calcium carbonate 400 mg-simethicone 40 mg: 2 tablets orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 2400 mg-simethicone 240 mg
-Duration of therapy: 2 weeks

Age-based dosing:
Younger than 2 years: Data not available

2 to 5 years:
Calcium carbonate 400 mg-simethicone 40 mg: 1 tablet orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 1200 mg-simethicone 120 mg (3 tablets)
-Duration of therapy: 2 weeks

6 to 11 years:
Calcium carbonate 400 mg-simethicone 40 mg: 2 tablets orally up to 3 times a day as needed or as directed
-Maximum dose: Calcium carbonate 2400 mg-simethicone 240 mg (6 tablets)
-Duration of therapy: 2 weeks

12 years and older:
Calcium carbonate 750 mg-simethicone 80 mg: 1 to 2 tablets orally up to 6 times a day as needed or as directed
-Maximum dose: Calcium carbonate 4500 mg-simethicone 480 mg (6 tablets)/day
-Duration of therapy: Up to 2 weeks

Calcium carbonate 1000 mg-simethicone 60 mg: 1 to 2 tablets orally up to 8 times a day as needed or as directed
-Maximum dose: Calcium carbonate 8000 mg-simethicone 480 mg (8 tablets)/day
-Duration of therapy: Up to 2 weeks

Comment: Patients should not use the maximum daily dose for longer than 2 weeks unless otherwise directed.

Uses:
-Relief of acid indigestion, heartburn, sour stomach, or upset stomach associated with these symptoms
-Relief of gas associated with acid indigestion, heartburn, or sour stomach
-Relief of bloating and pressure (gas)
-Relief of overindulgence in food and drink

Renal Dose Adjustments

Data not available

Patients with kidney stones: Consult with a health care provider prior to using the calcium carbonate 1000 mg-simethicone 60 mg tablet formulation.

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: None.

Safety and efficacy in calcium carbonate 400 mg-simethicone 40 mg have not been established in patients younger than 2 years or less than 10.9 kg.
Safety and efficacy in calcium carbonate 750 mg-simethicone 80 mg and calcium carbonate 1000 mg-simethicone 60 mg tablet formulations have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Storage requirements:
-Protect from moisture.
-Patients should avoid freezing chewable tablets.

Patient advice:
-Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
-Patients should be instructed to avoid using products if the tamper evident feature(s) are torn, broken, and/or missing.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.