Calcium carbonate / simethicone Pregnancy and Breastfeeding Warnings
Calcium carbonate / simethicone is also known as: Alka-Seltzer Heartburn + Gas, Alka-Seltzer Heartburn + Gas ReliefChews, Children's Mylicon, Gas-X with Maalox, Gas-X with Maalox Extra Strength, Maalox Advanced Maximum Strength Chewable, Maalox Junior Relief Chewable, Maalox Max Quick Dissolve, Rolaids Extra Strength Plus Gas Relief Softchews, Titralac Plus, Titralac Plus Liquid, Tums Chewy Bites with Gas Relief (Lemon & Strawberry), Tums Plus
Calcium carbonate / simethicone Pregnancy Warnings
Based on years of use, the malformative risk with calcium carbonate is unlikely in humans. In some patients, hypercalcemia has resulted in milk-alkali syndrome and other adverse events on the fetus. Animal studies using simethicone have not been reported. There are no controlled data in human pregnancy.
Benefit should outweigh risk.
US FDA pregnancy category: Not formally assigned to a pregnancy category.
Comments:
-Simethicone is not orally absorbed.
-Patients should limit their daily intake of calcium.
Calcium carbonate / simethicone Breastfeeding Warnings
Calcium is normally excreted in human milk.
The manufacturer makes no recommendation regarding use during lactation.
Excreted into human milk: Yes
Comments:
-Simethicone is not orally absorbed.
-Both drugs have been used without apparent harmful effects in the nursing infant.
References for pregnancy information
- "Product Information. Tums with Gas Relief Chewy Bites (calcium carbonate-simethicone)." GlaxoSmithKline Consumer Healthcare Holdings (US) LLC, Warren, NJ.
- Briggs GG, Freeman RK. "Drugs in Pregnancy and Lactation. 10th ed." Philadelphia, PA: Wolters Kluwer Health (2015):
References for breastfeeding information
- United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
- "Product Information. Tums with Gas Relief Chewy Bites (calcium carbonate-simethicone)." GlaxoSmithKline Consumer Healthcare Holdings (US) LLC, Warren, NJ.
- Briggs GG, Freeman RK. "Drugs in Pregnancy and Lactation. 10th ed." Philadelphia, PA: Wolters Kluwer Health (2015):
See Also...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
