Brompheniramine Dosage
Applies to the following strengths: 2 mg/5 mL; 12 mg; 8 mg; 4 mg; 6 mg; 8 mg/5 mL; 10 mg/mL; 11 mg; 10 mg/5 mL; 12 mg/5 mL; 4 mg/5 mL; 1 mg/mL; 2 mg/10 mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Cold Symptoms
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Adult Dose for Allergic Rhinitis
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Adult Dose for Urticaria
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Adult Dose for Allergic Reaction
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to mg 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
IV, IM, subcutaneous: 5 mg to 20 mg every 6 to 12 hours. Duration of action is 3 to 12 hours.
Maximum parenteral dose 40 mg/day.
Usual Pediatric Dose for Allergic Rhinitis
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 years:
Extended Release suspension:
2 mg orally twice daily, not to exceed 2 doses in 24 hours.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release suspension:
4 mg orally twice daily, not to exceed 2 doses in 24 hours.
> 12 years:
Immediate Release:
4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg sustained release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Pediatric Dose for Cold Symptoms
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 years:
Extended Release suspension:
2 mg orally twice daily, not to exceed 2 doses in 24 hours.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release suspension:
4 mg orally twice daily, not to exceed 2 doses in 24 hours.
> 12 years:
Immediate Release:
4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg sustained release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Pediatric Dose for Urticaria
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 years:
Extended Release suspension:
2 mg orally twice daily, not to exceed 2 doses in 24 hours.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release suspension:
4 mg orally twice daily, not to exceed 2 doses in 24 hours.
> 12 years:
Immediate Release:
4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg sustained release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Pediatric Dose for Allergic Reaction
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 yrs:
Extended Release Suspension:
2.5 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release Suspension:
5 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
> 12 years:
Immediate Release:
4 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
IM, IV, subcutaneous :
< 12 years:
0.5 mg/kg/day divided every 6 to 8 hours.
> 12 years:
5 mg to 20 mg every 6 to 12 hours. Duration of action is 3 to 12 hours.
Maximum parenteral dose 40 mg/day.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Brompheniramine should be used with caution in patients with asthma, heart disease, hypertension or thyroid disease.
Dialysis
Data not available
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