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Altoprev Dosage

Generic name: LOVASTATIN 20mg
Dosage form: tablet, extended release
Drug class: Statins

Medically reviewed by Last updated on Mar 14, 2024.

Important Dosage and Administration Information

Take Altoprev orally once daily in the evening.
The maximum recommended dosage of Altoprev is 60 mg orally once daily.
Swallow tablets whole. Do not split, crush, or chew the extended-release tablets [see Clinical Pharmacology (12.3)].
If as dose is missed, take the missed dose as soon as possible. Do not double the next dose.
The recommended dosage of Altoprev depends on a patient’s indication for usage, LDL-C level, and individual risk for cardiovascular events.
For patients that require a high-intensity statin or are unable to achieve their LDL-C goal receiving Altoprev 60 mg daily, prescribe alternative LDL-C-lowering treatment.
Assess LDL-C when clinically appropriate, as early as 4 weeks after initiating Altoprev, and adjust the dosage if necessary.

Recommended Dosage in Adult Patients

The recommended dosage range of Altoprev is 20 to 60 mg once daily in the evening.

Recommended Dosage in Patients with Renal Impairment

In patients with severe renal impairment [creatinine clearance (CLcr) <30 mL/min], consider if the benefits of increasing the dosage above 20 mg daily outweighs the increased risk of myopathy and rhabdomyolysis [see Warnings and Precautions (5.1) and Use in Specific Populations (8.6)].
There are no dosage adjustment recommendations for patients with mild or moderate renal impairment.

Dosage Modifications Due to Drug Interactions

Concomitant use of Altoprev with the following drugs requires dosage modification of Altoprev [see Warnings and Precautions (5.1) and Drug Interactions (7.1)].

Patients Taking Danazol, Diltiazem, Dronedarone, or Verapamil

Do not exceed Altoprev 20 mg daily.

Patients Taking Amiodarone

Do not exceed Altoprev 40 mg daily.

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.