Comparing Wellbutrin vs Zyban
| Wellbutrin (bupropion) | Zyban (bupropion) |
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| Wellbutrin (bupropion) | Zyban (bupropion) |
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Prescription only
Wellbutrin may be used in the treatment of depression; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black box warning because it may cause... View more |
Prescription only
Prescribed for Smoking Cessation. Zyban may also be used for purposes not listed in this medication guide. |
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| More about Wellbutrin (bupropion) | More about Zyban (bupropion) | |
| Ratings & Reviews | ||
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Wellbutrin has an average rating of 6.8 out of 10 from a total of 763 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
Zyban has an average rating of 8.0 out of 10 from a total of 129 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
View all Wellbutrin side effects |
View all Zyban side effects |
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| Drug Class | ||
| Generic Availability | ||
| Lower cost generic approved | ||
| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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| Brand Names | ||
| Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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30 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 560 drugs are known to interact with Wellbutrin:
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A total of 560 drugs are known to interact with Zyban:
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| Alcohol/Food/Lifestyle Interactions | ||
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| Disease Interactions | ||
| First Approval Date | ||
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December 30, 1985 |
May 14, 1997 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.