Trihexyphenidyl Alternatives Compared
| Trihexyphenidyl | Benztropine | Amantadine |
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| Trihexyphenidyl | Benztropine | Amantadine |
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Prescription only
Prescribed for Parkinson's Disease, Extrapyramidal Reaction, Cerebral Spasticity. Trihexyphenidyl may also be used for purposes not listed in this medication guide. |
Prescription only
Benztropine may be used to treat symptoms of Parkinson's disease or alleviate side effects that affect movement caused by antipsychotics. However, it may cause unwanted effects such as blurred... View more |
Prescription only
Amantadine may be used to treat dyskinesia or reduce the number of OFF episodes in those with Parkinson's disease (PD) OR in the treatment or prevention of Influenza A viral infection. Nausea... View more |
Related suggestions Extrapyramidal Reaction
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| More about Trihexyphenidyl | More about Benztropine | More about Amantadine | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Trihexyphenidyl has an average rating of 6.5 out of 10 from a total of 24 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 25% reported a negative effect. |
Benztropine has an average rating of 6.8 out of 10 from a total of 39 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 28% reported a negative effect. |
Amantadine has an average rating of 6.9 out of 10 from a total of 56 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Trihexyphenidyl side effects |
View all Benztropine side effects |
View all Amantadine side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Trihexyphenidyl prices |
View all Benztropine prices |
View all Amantadine prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Trihexy |
N/A |
Gocovri, Osmolex ER | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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4.1 hours |
N/A |
19 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 337 drugs are known to interact with Trihexyphenidyl:
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A total of 346 drugs are known to interact with Benztropine:
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A total of 131 drugs are known to interact with Amantadine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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May 13, 1949 |
March 05, 1954 |
February 14, 1968 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.