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Trihexyphenidyl Pregnancy and Breastfeeding Warnings

Trihexyphenidyl is also known as: Artane, Trihexane, Trihexy

Medically reviewed on December 15, 2017

Trihexyphenidyl Pregnancy Warnings

Trihexyphenidyl has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in animal or human pregnancy. Trihexyphenidyl is only recommended for use during pregnancy when need has been clearly established and benefit outweighs risk.

In a large prospective study of 2323 exposures during the first trimester, atropine-related drugs as a whole were possibly associated with minor fetal malformations. However, only 9 of those exposures were to trihexyphenidyl.

See references

Trihexyphenidyl Breastfeeding Warnings

There are no data on the excretion of trihexyphenidyl into human milk.

See references

References for pregnancy information

  1. "Product Information. Artane (trihexyphenidyl)." Lederle Laboratories, Wayne, NJ.
  2. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):

References for breastfeeding information

  1. "Product Information. Artane (trihexyphenidyl)." Lederle Laboratories, Wayne, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.