Comparing Rizatriptan vs Sumatriptan

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Rizatriptan

Sumatriptan

Prescription only

Prescribed for Migraine, Headache. Rizatriptan may also be used for purposes not listed in this medication guide.

Prescription only

Sumatriptan may be used to quickly relieve the symptoms of a migraine but may not be suitable for everyone including those with pre-existing cardiovascular conditions. Prescribed for Cluster... View more

More about Rizatriptan

More about Sumatriptan

Ratings & Reviews

Rizatriptan has an average rating of 8.3 out of 10 from a total of 339 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 12% reported a negative effect.

Sumatriptan has an average rating of 7.7 out of 10 from a total of 549 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 17% reported a negative effect.

View all 339 reviews

View all 549 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Drowsiness (11.8%)
Nausea (9.4%)
Tiredness (7.7%)
Dizziness (6.5%)
Sleepy (5.3%)
Pain (3.5%)
Anxiety (2.7%)

View all Rizatriptan side effects

Nausea (13.5%)
Drowsiness (6.6%)
Pain (6.4%)
Chest pain (5.1%)
Dizziness (5.1%)
Vomiting (4.4%)
Tiredness (4.2%)

View all Sumatriptan side effects

Drug Class

Antimigraine agents

Antimigraine agents

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	12 each
Strength	10 mg
Per unit^*	$1.52 - $10.56
Cost^*	$18.19 - $126.67

View all Rizatriptan prices

Quantity	0.5 mL
Strength	6 mg/0.5 mL
Per unit^*	$41.00 - $105.76
Cost^*	$20.50 - $52.88

View all Sumatriptan prices

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Dosage Forms

Oral tablet
Oral tablet, disintegrating

Nasal spray
Oral tablet
Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

6 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 156 drugs are known to interact with Rizatriptan:

71 major drug interactions (292 brand and generic names)
29 moderate drug interactions (161 brand and generic names)
56 minor drug interactions (345 brand and generic names)

A total of 100 drugs are known to interact with Sumatriptan:

70 major drug interactions (280 brand and generic names)
30 moderate drug interactions (166 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

June 29, 1998

January 28, 2016

WADA Class View classifications

N/A

More Information

Patient Resources

Rizatriptan uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Rizatriptan vs Sumatriptan

See also:

Ubrelvy

Nurtec ODT

Qulipta

Paracetamol

Tylenol

Celebrex

Botox

Topamax

Advil

Reglan

Further information

Comparing Rizatriptan vs Sumatriptan

See also:

Further information

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