Comparing Rexulti vs Spravato
Rexulti (brexpiprazole) | Spravato (esketamine) |
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Rexulti (brexpiprazole) | Spravato (esketamine) |
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Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression. Spravato may also be used for purposes not listed in this medication guide. |
Related suggestions Depression
Major Depressive Disorder
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More about Rexulti (brexpiprazole) | More about Spravato (esketamine) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Rexulti has an average rating of 6.6 out of 10 from a total of 496 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 25% reported a negative effect. |
Spravato has an average rating of 6.3 out of 10 from a total of 125 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 29% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Rexulti side effects |
View all Spravato side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Rexulti prices |
View all Spravato prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
N/A |
N/A |
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Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
91 hours |
12 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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Pregnancy Category | |||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 601 drugs are known to interact with Rexulti:
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A total of 296 drugs are known to interact with Spravato:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
July 10, 2015 |
N/A |
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WADA Class View classifications | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Cymbalta
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Zyprexa
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.