Spravato Interactions
There are 296 drugs known to interact with Spravato (esketamine), along with 4 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 266 are major, and 30 are moderate.
- View all 296 medications that may interact with Spravato
- View Spravato alcohol/food interactions (2)
- View Spravato disease interactions (4)
Most frequently checked interactions
View interaction reports for Spravato (esketamine) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- albuterol
- amitriptyline
- Auvelity (bupropion / dextromethorphan)
- baclofen
- bupropion
- buspirone
- clonazepam
- clonidine
- Cymbalta (duloxetine)
- famotidine
- gabapentin
- hydroxyzine
- ibuprofen
- lamotrigine
- levothyroxine
- melatonin
- metformin
- omeprazole
- ondansetron
- pantoprazole
- propranolol
- Rexulti (brexpiprazole)
- tizanidine
- trazodone
- Trintellix (vortioxetine)
- Vitamin D3 (cholecalciferol)
- Vraylar (cariprazine)
- Vyvanse (lisdexamfetamine)
Spravato alcohol/food interactions
There are 2 alcohol/food interactions with Spravato (esketamine).
Spravato disease interactions
There are 4 disease interactions with Spravato (esketamine) which include:
Report options
More about Spravato (esketamine)
- Spravato consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (125)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: miscellaneous antidepressants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Lexapro
Lexapro is used to treat anxiety and major depressive disorder. Learn about side effects ...
Rexulti
Rexulti (brexpiprazole) is a prescription antipsychotic medication used in the treatment of major ...
Zoloft
Zoloft is an antidepressant used to treat major depression, obsessive-compulsive disorder, panic ...
Seroquel
Seroquel is used to treat the symptoms of schizophrenia, bipolar disorder and major depressive ...
Prozac
Prozac (fluoxetine) is an SSRI antidepressant used to treat depression, OCD, panic disorder ...
Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Wellbutrin
Wellbutrin (bupropion) is used to treat major depressive disorder and seasonal affective disorder ...
Celexa
Celexa (citalopram) is an antidepressant in a group of drugs called selective serotonin reuptake ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
