Comparing Promethazine vs Xanax
| Promethazine | Xanax (alprazolam) |
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| Promethazine | Xanax (alprazolam) |
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Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
Prescription only
Xanax may be used for the treatment of anxiety or panic disorder; however, it is addictive, and withdrawal symptoms can be severe. Can interact with several drugs including those that cause... View more |
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| More about Promethazine | More about Xanax (alprazolam) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Promethazine has an average rating of 7.3 out of 10 from a total of 395 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
Xanax has an average rating of 8.6 out of 10 from a total of 921 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 9% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Promethazine side effects |
View all Xanax side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Promethazine prices |
View all Xanax prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | Other alprazolam brands include: Alprazolam Intensol, Xanax XR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
20 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 690 drugs are known to interact with Promethazine:
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A total of 563 drugs are known to interact with Xanax:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 29, 1951 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.