Comparing Progesterone vs Vagifem
| Progesterone | Vagifem (estradiol) |
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| Progesterone | Vagifem (estradiol) |
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Prescription and OTC
Progesterone is a hormone that is used to treat conditions associated with ovulation, fertility, menstruation, menopause, or abnormal uterine bleeding. It may be used in gender-affirming therapy to... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Vagifem may also be used for purposes not listed in this medication guide. |
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| More about Progesterone | More about Vagifem (estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Progesterone has an average rating of 6.5 out of 10 from a total of 78 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 21% reported a negative effect. |
Vagifem has an average rating of 6.0 out of 10 from a total of 102 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Progesterone side effects |
View all Vagifem side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Progesterone prices |
View all Vagifem prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | Other estradiol brands include: Estrace Vaginal Cream, Estring, Imvexxy, Yuvafem | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1 hour |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 218 drugs are known to interact with Progesterone:
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A total of 258 drugs are known to interact with Vagifem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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November 01, 1974 |
March 26, 1999 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
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Clomid
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Prometrium
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Pregnyl
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Menopur
Menopur is used for female infertility, follicle stimulation, ovulation induction
Bijuva
Bijuva (estradiol and progesterone) is used to reduce moderate to severe hot flashes in menopausal ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.