Comparing Phentermine vs Rybelsus
| Phentermine | Rybelsus (semaglutide) |
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| Phentermine | Rybelsus (semaglutide) |
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Prescription only
Phentermine may be used short-term as an aid to weight loss; however, it can be addictive and tolerance may develop to its weight-losing effects, rendering it less effective with time. Prescribed for... View more |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
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| More about Phentermine | More about Rybelsus (semaglutide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Phentermine has an average rating of 8.6 out of 10 from a total of 3014 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 5% reported a negative effect. |
Rybelsus has an average rating of 6.4 out of 10 from a total of 288 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Phentermine side effects |
View all Rybelsus side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Phentermine prices |
View all Rybelsus prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Adipex-P, Atti-Plex P, Lomaira | Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 196 drugs are known to interact with Phentermine:
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A total of 273 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 14, 1973 |
September 20, 2019 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Mounjaro
Mounjaro (tirzepatide) is FDA-approved to manage type 2 diabetes in adults. It lowers blood sugar ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
Wegovy
Wegovy is a once-weekly semaglutide injection used for chronic weight management and to reduce ...
Victoza
Victoza helps control blood sugar levels and reduce the risk of serious heart problems in people ...
Contrave
Contrave is an anorexiant and is used to help manage weight in obese or overweight adults with ...
Saxenda
Saxenda (liraglutide) injection is used for weight loss in obese or overweight patients. Includes ...
Qsymia
Qsymia (phentermine and topiramate) is used together with diet and exercise to treat obesity ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.