Comparing Pentobarbital vs Primidone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Pentobarbital	Primidone	Enter another drug to compare

Pentobarbital

Primidone

Prescription only

Prescribed for Sedation, Status Epilepticus, Insomnia. Pentobarbital may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Benign Essential Tremor, Epilepsy, Seizures. Primidone may also be used for purposes not listed in this medication guide.

More about Pentobarbital

More about Primidone

Ratings & Reviews

Pentobarbital has an average rating of 7.0 out of 10 from a total of 4 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 0% reported a negative effect.

Primidone has an average rating of 6.0 out of 10 from a total of 109 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 28% reported a negative effect.

View all 4 reviews

View all 109 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Pentobarbital side effects

Dizziness (14.7%)
Tremors (11.0%)
Drowsiness (7.3%)
Nausea (7.3%)
Tiredness (7.3%)
Disorientation (4.6%)
Brain fog (3.7%)

View all Primidone side effects

Drug Class

Barbiturates

Barbiturate anticonvulsants

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	20 mL
Strength	50 mg/mL
Per unit^*	$51.32 - $51.33
Cost^*	$1,026.40 - $1,026.61

View all Pentobarbital prices

Quantity	100 each
Strength	50 mg
Per unit^*	$0.25
Cost^*	$24.57

View all Primidone prices

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Dosage Forms

Injectable solution

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

50 hours

12 hours

CSA Schedule ¹ View glossary of CSA terms

Multiple

The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category N Not classified

See the full pregnancy warnings document.

Drug Interactions

A total of 555 drugs are known to interact with Pentobarbital:

37 major drug interactions (175 brand and generic names)
490 moderate drug interactions (2460 brand and generic names)
28 minor drug interactions (98 brand and generic names)

A total of 687 drugs are known to interact with Primidone:

238 major drug interactions (705 brand and generic names)
420 moderate drug interactions (2766 brand and generic names)
29 minor drug interactions (105 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Ask your doctor before using PENTobarbital together with alcohol, this can add to dizziness... View more

Ask your doctor before using primidone together with alcohol, this can add to dizziness, drowsiness... View more

Disease Interactions

First Approval Date

N/A

March 08, 1954

WADA Class View classifications

N/A

More Information

Patient Resources

Pentobarbital uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Pentobarbital vs Primidone

See also:

Ativan

Atarax

Dupixent

Vistaril

Phenergan

Desyrel

Phenobarbital

Fentanyl

Promethazine

Lorazepam

Further information

Comparing Pentobarbital vs Primidone

See also:

Further information

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