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Primidone and Nausea: What Users Say

Brand names: Mysoline

Nausea: mentioned by 8 users (7.3%)

Based on user experiences from 109 Primidone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 14.7%
tremors 11.0%
drowsiness 7.3%
nausea 7.3%
tiredness 7.3%
disorientation 4.6%
brain fog 3.7%
depression 3.7%
fatigue 3.7%
irritability 2.8%

Reviews for Primidone

Commonly mentioned side effects
  • CMy...
  • October 3, 2014

For Benign Essential Tremor "For Essential Tremor. Took me a long time to get used to side effects. Felt scared. Dizzy. Headache. Nausea. Increased heart rate. Anxious. Barely standing because I started too high at 50mg. Need to start very low for me. I finally got better. No shakes. Very pleased. The Neurologist's office kept rescheduling me, and I ran out. This second time starting was even more AWFUL. Flu-like, plus feeling kind of like I was in a total mental fog. Odd. Be cautious is my opinion. I was in misery for 3 days. Unable to function. Finally getting better. Day 5. Should have taken at bedtime. Never knew."

7 / 10
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  • Gra...
  • May 19, 2016

For Benign Essential Tremor "After taking a half of a tiny pill of Primidone for 4 nights at bedtime, I could not walk down the hall when I woke up. I was falling everywhere & was so nauseated. I had horrible nightmares that woke me up screaming! First thing Monday morning, I called the neurologist who had prescribed it, and the receptionist would not let me talk to her. She said she would call me back. She did not call, so I called again later in the day. Still would not let me talk to the doctor but told me she said, 'never take it again.' My primary care doctor sent me to see a specialist who checked my eyes, hearing, and a lot of things with his special machines. He determined that it was the Primidone that was causing the problems. (Of course, I never took it again.) Bt"

1 / 10
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74 Report
  • Anonymous
  • December 9, 2009

For Benign Essential Tremor "I was diagnosed with ET 6 weeks ago. I was prescribed Primidone. To date, I still am having serious side effects. My tremors are continual, even to the point where my left arm feels 'dead'. Generally, I feel drained, dizzy, and sick to my stomach. My voice is halting, with shaky patterns, and is more affected when I am tired. I find it very difficult to take this medicine and will be calling my doctor to discuss any other options."

3 / 10
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100 Report
  • Anonymous
  • December 9, 2009

For Benign Essential Tremor "I was diagnosed with ET 6 weeks ago. I was prescribed Primidone. To date, I still am having serious side effects. My tremors are continual, even to the point where my left arm feels 'dead'. Generally, I feel drained, dizzy, and sick to my stomach. My voice is halting, with shaky patterns, and is more affected when I am tired. I find it very difficult to take this medicine and will be calling my doctor to discuss any other options."

3 / 10
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100 Report
  • kha...
  • Taken for less than 1 month
  • May 3, 2016

For Benign Essential Tremor "I am a 31-year-old male. Just figured out I have ET. I could not take propranolol due to asthma. Doctor prescribed 1/4 of 250 mg primidone (Mysoline) at bedtime at night. I had horrible side effects the next morning. Head spinning sensation plus nauseated all day long. Hands felt numb. Tremor was controlled, though, by some amount. But too many side effects to continue. Doctor changed it to topiramate. Today is the first day I am taking topiramate."

3 / 10
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35 Report

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  • Anonymous
  • Taken for less than 1 month
  • September 12, 2019

For Benign Essential Tremor "I am an 86-year-old male in excellent health, except for moderate essential tremors in my hands and neck. For the first time, I took 50 mg of Primidone after breakfast at 8:00 AM. After 1 1/2 hours, I got so dizzy and nauseated that I could not walk. I also had periods of double vision. I spent the rest of the day and night in bed. After 24 hours, the effect is about 80% gone. No more Primidone! I'd rather shake than stagger."

1 / 10
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24 Report
  • Hop...
  • Taken for less than 1 month
  • October 13, 2021

For Benign Essential Tremor "I was prescribed this drug nearly 4 weeks ago by my neurologist as I have essential tremor. I had to start at 1/4 tablet x 2 a day and then increased to 1/2 tablet (125 mg) x 2 a day. I take other meds for depression and glaucoma (which he knows about). The first night was awful - nightmares, woke up feeling drowsy (a side effect). It became so bad for me that I was falling over at night, nightmares, and feeling foggy/drowsy/nauseous/more depressed/vertigo, and my eyes not being able to focus properly during the day, and my work suffered. My tremors improved, but I can't deal with the side effects, so I have started to slowly wean myself off this drug. I phoned and left a message for my neurologist, but he hasn't returned my call. My tremors are returning, but I still have some side effects. Perhaps if I wasn't working and persevered, the side effects would go with more time."

2 / 10
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  • Rog...
  • Taken for less than 1 month
  • February 27, 2017

For Benign Essential Tremor "Issues with tremors of the trapezius muscles (bobblehead). Dizziness, nausea within 30 minutes of taking the first dose. Currently, only medication on my list of 'Medications allergic to.'"

1 / 10
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11 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.