Opium Alternatives Compared
| Opium | Loperamide | Lomotil (atropine / diphenoxylate) |
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| Opium | Loperamide | Lomotil (atropine / diphenoxylate) |
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Prescription only
Prescribed for Diarrhea. Opium may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Loperamide effectively treats diarrhea in adults and children over the age of 2 years by slowing down the movement of the bowel. Children are especially sensitive to its effects, especially if they... View more |
Prescription only
Prescribed for Diarrhea. Lomotil may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Opium | More about Loperamide | More about Lomotil (atropine / diphenoxylate) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Opium has an average rating of 9.6 out of 10 from a total of 30 ratings on Drugs.com. 97% of reviewers reported a positive effect, while 0% reported a negative effect. |
Loperamide has an average rating of 8.4 out of 10 from a total of 94 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 10% reported a negative effect. |
Lomotil has an average rating of 8.0 out of 10 from a total of 49 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Opium side effects |
View all Loperamide side effects |
View all Lomotil side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Opium prices |
View all Loperamide prices |
View all Lomotil prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium, Imodium A-D, Kaopectate II, Neo-Diaral, Up and Up Anti-Diarrheal Solution View more | Other atropine / diphenoxylate brands include: Logen, Lomanate | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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4 hours |
10.8 hours |
14 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Multiple
The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 424 drugs are known to interact with Opium:
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A total of 356 drugs are known to interact with Loperamide:
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A total of 316 drugs are known to interact with Lomotil:
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| First Approval Date | ||||||||||||||||||||||||||
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N/A |
N/A |
September 15, 1960 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.