Lomotil Dosage
Generic name: DIPHENOXYLATE HYDROCHLORIDE 2.5mg, ATROPINE SULFATE 0.025mg
Dosage form: tablet
Drug class: Antidiarrheals
Medically reviewed by Drugs.com. Last updated on Apr 3, 2025.
Management of Diarrhea in Patients 13 Years of Age and Older
Lomotil is recommended as adjunctive therapy for the management of diarrhea in patients 13 years of age and older. Consider the nutritional status and degree of dehydration in patients prior to initiating therapy with Lomotil. The use of Lomotil should be accompanied by appropriate fluid and electrolyte therapy, when indicated. If severe dehydration or electrolyte imbalance is present, do not administer Lomotil until appropriate corrective therapy has been indicated (see WARNINGS).
Initial and Maximum Recommended Dosage in Patients 13 Years of Age and Older
The initial adult dosage is 2 Lomotil tablets four times daily (maximum total daily dose of 20 mg per day of diphenoxylate hydrochloride). Most patients will require this dosage until initial control of diarrhea has been achieved. Clinical improvement of acute diarrhea is usually observed within 48 hours.
Frequently asked questions
More about Lomotil (atropine / diphenoxylate)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (49)
- Drug images
- Side effects
- During pregnancy
- Generic availability
- Support group
- Drug class: antidiarrheals
- En español
Patient resources
- Lomotil drug information
- Lomotil (Diphenoxylate and Atropine Solution)
- Lomotil (Diphenoxylate and Atropine Tablets)
Other brands
Professional resources
Related treatment guides
See also:
Xifaxan
Xifaxan (rifaximin) is used to treat travelers' diarrhea, irritable bowel syndrome with diarrhea ...
Pepto-Bismol
Pepto-Bismol is antacid used to treat heart burn, indigestion, diarrhea, gas or an upset stomach ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Viberzi
Viberzi (eluxadoline) is used to treat irritable bowel Syndrome with Diarrhea (IBS-D). Includes ...
Lotronex
Lotronex is used to treat severe, chronic irritable bowel syndrome (IBS) in women. Learn about side ...
Bismuth subsalicylate
Bismuth subsalicylate systemic is used for diarrhea, diarrhea, acute, diarrhea, chronic ...
Neomycin
Neomycin systemic is used for bowel preparation, diarrhea, hepatic coma, hepatic encephalopathy
Rifaximin
Rifaximin systemic is used for crohn's disease, diarrhea, diarrhea, chronic, hepatic ...
Loperamide
Loperamide is an anti-diarrheal medication used to treat diarrhea and reduce stool output in ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
